表面多孔聚醚醚酮的制备和压缩性能——一种理想的融合材料  

Fabrication method and compressive property of surface-porous polyetheretherketone(PEEK) : an optimal interbody fusion material

作　　者：张云霞 李秋炎 王东 何国[1] ZHANG Yunxia;LI Qiuyan;WANG Dong;HE Guo(College of Materials Science and Engineering,Shanghai Jiaotong University,Shanghai 200240,China)

机构地区：[1]上海交通大学材料科学与工程学院,上海200240

出　　处：《生物医学工程研究》2018年第1期61-65,共5页Journal Of Biomedical Engineering Research

摘　　要：为了满足聚醚醚酮(poly ether ether ketone,PEEK)融合器在高应力环境下的应用,同时提高其与骨组织的接合能力,采用压铸和腐蚀方法制备孔径为0.4 mm,多孔层厚度为1.5 mm,开孔率达100%的表面多孔PEEK(surface porous-PEEK,SP-PEEK),并研究了SP-PEEK的单向压缩行为。结果显示:当SPPEEK孔隙率分别为30%,40%和50%时,其在横向力(平行于多孔层方向)作用下,保留了实体PEEK53.6%~83.6%的弹性模量(分别为9.2、7.9和5.9 GPa)及87.1%~90.5%的屈服强度(分别为57、55.8和54.9 MPa);在轴向力(垂直于多孔层方向)作用下,SP-PEEK保留了47.1%~49.1%的弹性模量(分别为5.4、5.3和5.2 GPa)及64.3%~79%的屈服强度(分别为49.8、48.3和40.5 MPa)。制备的SP-PEEK具有与皮质骨相当的弹性模量(4.9~28 GPa),能够满足脊柱融合的刚度要求。In order to improve interface integration between bone and poly ether ether ketone(PEEK)cage,PEEK was modified with a surface porous layer by die casting and etching process.Porous layer with 100%open porosity possessed a pore size of 400 jjim and thickness of 1.5 mm.Under transverse force(parallel to porous layer),uni-axial compression tests showed that surface porous PEEK(SP-PEEK)with porosities of 30%,40%and 50%preserved 87.1%-90.5%of the strength(57,55.8 and 54.9 MPa respectively)and 53.6%~83.6%of the elastic modulus(9.2,7.9 and 5.9 GPa respectively)of solid injection-molded PEEK.Under axial force(perpendicular to porous layer),SP-PEEK with porosities of 30%,40%and 50%preserved 64.3%?79%of the compressive yield strength(49.8,48.3 and 40.5 MPa respectively)and 47.1~49.1%of the elastic modulus(5.4,5.3 and 5.2GPa respectively)of solid PEEK.As-prepared SP-PEEK possessed comparable stiffness with cortical bone(4.9~28GPa),suggesting that SP-PEEK can maintain stiffness necessary for interbody fusion.

关 键 词：聚醚醚酮 表面多孔材料 脊柱融合 压缩行为 高应力环境 

分 类 号：R318[医药卫生—生物医学工程]