尿道狭窄内切开术后腔内放疗临床研究  

Clinical study of intracavitary brachytherapy after transurethral incision for urethral stenosis

作　　者：赵淑红[1] 黄凤仙[1] 靳荣辉 高晖[1] 杜春[2] Zhao Shuhong;Huang Fengxian;Jin Ronghui(Department of Radiation of Shaanxi Provincial People’s Hospital,Xi’an 710068)

机构地区：[1]陕西省人民医院放疗科,西安710068 [2]陕西省人民医院泌尿外科,西安710068

出　　处：《陕西医学杂志》2018年第4期436-438,共3页Shaanxi Medical Journal

摘　　要：目的:评价尿道狭窄内切开术后腔内放疗的疗效。方法:73例尿道狭窄术后患者随机分为放疗组34例和观察组39例,放疗组术后24h内开始192铱腔内放疗,剂量1200~1500cGy;观察组密切随诊观察。结果:中位随访时间26月(18~41月),放疗组和观察组复发率分别为11.76%和48.72%(P=0.001);放疗组和观察组平均复发时间分别为30.25月和20.74月(P=0.041);未见有尿道癌的发生。结论:尿道狭窄内切开术后的腔内放疗可降低尿道狭窄的复发率,延迟复发时间,近期疗效满意。Objective:To evaluate the effect of intracavitary brachytherapy after transurethral incision for urethral stenosis.Methods:73 patients after transurethral incision for urethral stenosis were randomly divided into the radiotherapy group(34 participants)and the observation group(39 participants).The radiotherapy group have been treated by intracavitary brachytherapy with 192 Ir within 24 hours after operation,the irradiation dose was 1200～1500 cGy;The observation group followed up observation.Results:The median follow-up time of 26 months(18～41 months),the recurrence rates of the radiotherapy group and observation group were 11.76%vs 48.72%(P=0.001);The mean recurrence times of the radiotherapy group and observation group were 30.25 months vs 20.74 months(P=0.041);No urethral cancer was observed.Conclusion:Intracavitary brachytherapy after transurethral incision can reduced recurrence rates and dalayed recurrence times for urethral stenosis,the recent effect is satisfied.

关 键 词：尿道狭窄 放射疗法 @192铱 

分 类 号：R695[医药卫生—泌尿科学]