女性泌尿生殖道支原体感染状况及耐药分析  

Analysis of mycoplasma infection and drug resistance in female genitourinary tract

作　　者：高爽[1] GAO Shuang(Department of Clinical Laboratory,Shenyang Maternity and Infant Hospital,Shenyang 110011,China)

机构地区：[1]沈阳市妇婴医院检验科,110011

出　　处：《中国现代药物应用》2018年第6期27-28,共2页Chinese Journal of Modern Drug Application

基　　金：辽宁省自然科学基金项目(项目编号:20170540839)

摘　　要：目的分析妇科泌尿生殖道支原体感染的分布及耐药情况。方法回顾性分析576例泌尿生殖道感染患者的支原体培养及药敏试验结果。结果 576份送检标本共检出支原体333份,阳性率为57.8%。333份阳性标本中,单纯感染解脲支原体(Uu)感染、单纯感染人型支原体(Mh)以及Uu合并Mh感染所占比例分别是50.2%、0.9%和6.8%。333份支原体药敏结果显示:Uu、Uu+Mh、Mh对药物的敏感性不同,对强力霉素、美满霉素、交沙霉素、壮观霉素的敏感率均较高,对环丙沙星和氧氟沙星的耐药率较高。结论泌尿生殖道支原体以单纯Uu感染为主,强力霉素、美满霉素、交沙霉素、壮观霉素可作为治疗支原体的首选药物。Objective To analyze the distribution and drug resistance of mycoplasma infection in gynecologic genitourinary tract.Methods The results of mycoplasma culture and drug sensitivity test in 576 patients with genitourinary tract infection were analyzed retrospectively.Results A total of 333 mycoplasma were detected in 576 samples,with positive rate as 57.8%.In 333 positive samples,the infection rates of Ureaplasma urealyticum(Uu),Mycoplasma hominis(Mh)and Un combined with Mh were 50.2%,0.9%and 6.8%respectively.According to 333 Mycoplasma drug susceptibility test results,Uu,Uu+Mh and Mh shows different sensitivity to drugs,with higher sensitive rate to doxycycline,minocycline,josamycin,spectinomycin and higher resistant rate to ciprofloxacin and ofloxacin.Conclusion Genitourinary tract mycoplasma is mainly simple Uu infection,and doxycycline,minocycline,josamycin,spectinomycin can be the first choice for the the treatment of mycoplasma.

关 键 词：泌尿生殖道 支原体感染 耐药率 

分 类 号：R446.5[医药卫生—诊断学] R691.3[医药卫生—临床医学]