急性心肌梗死患者血清BNP、Hcy、hs-CRP与甲状腺激素变化的检验分析  

Analysis of serum BNP, Hcy, hs-CRP and thyroid hormone levels in patients with acute myocardial infarction

作　　者：张鑫[1] 闫业军[1] ZHANG Xin;YAN Yejun(Cardiology Department,Baoji Central Hospital,Baoji 721008,China)

机构地区：[1]宝鸡市中心医院心内科,陕西宝鸡721008

出　　处：《临床医学研究与实践》2017年第36期34-35,共2页Clinical Research and Practice

基　　金：国家自然科学基金资助项目(No.30770823)

摘　　要：目的研究血清BNP、Hcy、hs-CRP、甲状腺激素水平对急性心肌梗死的预测价值。方法选取2013年3月至2015年3月我院收治的急性心肌梗死患者80例,其中急性ST抬高型心肌梗死(STEMI)组49例,非急性ST抬高型心肌梗死(NSTEMI)组31例;并选取同时期收治的心功能正常的健康志愿者共80例作为对照组。对比不同类型急性心肌梗死患者及对照组的血清BNP、Hcy、hs-CRP、甲状腺激素水平,并分析BNP水平与梗死部位及梗死次数的相关性。结果急性心肌梗死组、STEMI组及NSTEMI组患者的T3水平均低于对照组,且STEMI组的T3水平低于NSTEMI组(P<0.05)。急性心肌梗死组患者的血清BNP,Hcy,hs-CRP水平明显高于对照组(P<0.05)。NSTEMI患者的BNP水平明显低于STEMI组(P<0.05);不同梗死部位患者的BNP水平无显著差异(P>0.05);再发梗死患者的BNP水平明显高于初次梗死患者(P<0.05)。结论急性心肌梗死患者血清BNP、Hcy、hs-CRP水平会出现明显升高,且甲状腺激素水平也会出现明显变化,其可用于判断患者心肌梗死的严重程度。Objective To study the predictive value of serum BNP,Hcy,hs-CRP and thyroid hormone levels in patients with acute myocardial infarction.Methods From March 2013 to March 2015,80 patients with acute myocardial infarction in our hospital were selected,including 49 cases of acute ST elevation myocardial infarction(STEMI)and 31 cases of non acute ST elevation myocardial infarction(NSTEMI).A total of 80 healthy volunteers with normal cardiac function in the same period were selected as the control group.The levels of serum BNP,Hcy,hs-CRP and thyroid hormone in patients with different types of acute myocardial infarction and control group were compared.The correlation between BNP levels and the infarction sites and infarctions numbers were analyzed.Results The T3 levels in the acute myocardial infarction group,STEMI group and NSTEMI group were lower than that of the control group,and T3 level in the STEMI group was lower than that of the NSTEMI group(P<0.05).The levels of serum BNP,Hcy and hs-CRP in the acute myocardial infarction group were significantly higher than those of the control group(P<0.05).The BNP level in the NSTEMI group was significantly lower than that of the STEMI group(P<0.05).There was no significant difference in the BNP levels in patients with different infarction sites(P>0.05).The BNP level in the recurrent infarction was higher than that of the initial infarction(P<0.05).Conclusion Serum BNP,Hcy,hs-CRP levels in patients with acute myocardial infarction will significantly increase,and the thyroid hormone levels in patients with acute myocardial infarction will change,and that can be used to determine the severity of myocardial infarction.

关 键 词：急性心肌梗死 BNP HCY HS-CRP 甲状腺激素 

分 类 号：R542.22[医药卫生—心血管疾病]