冠状动脉慢血流患者危险因素分析  

Risk Factors of Coronary Slow Flow

作　　者：卢聪[1] 周敏 赵龙宝 陈航[1] 张俊[1] 刘童[1] LU Cong;ZHOU Min;ZHAO Long-bao;CHEN Hang;ZHANG Jun;LIU Tong(Department of Cardiology,Chengdu First People’s Hospital,Chengdu 610000,China)

机构地区：[1]成都市第一人民医院心血管内科,成都610000

出　　处：《微循环学杂志》2018年第1期28-32,共5页Chinese Journal of Microcirculation

基　　金：四川省成都市科技惠民项目(2015-HM01-00106-SF);成都市医学科研课题(2015038)

摘　　要：目的:回顾性分析冠状动脉慢血流(CSF)患者的相关危险因素。方法:纳入2015-01—2016-09于本院行冠脉造影检查未见明显狭窄患者307例,采用校正的TIMI(Thrombolysis in Myocardial Infarction)血流分级方法将其分为CSF组(n=183)和正常对照组(n=124),比较两组间临床和实验室指标,对有差异者进行多因素Logistic回归分析CSF危险因素,同时分析有关指标与慢血流冠脉支数的相关性。结果:CSF组的男性比例、吸烟比例,血红蛋白(HGB)、红细胞压积(HCT)和血肌酐(SCr)水平均明显高于对照组(P<0.05)。Logistic回归分析显示,较高HCT(OR=1.083,95%CI 1.020-1.150,P=0.009)和男性(OR=1.857,95%CI 1.074-3.213,P=0.027)为CSF的独立危险因素。Spearman相关分析表明男性以及HCT和HGB水平与CSF冠脉支数均呈非常显著正相关。结论:男性激素及较高的HCT水平可能参与CSF的病理生理过程。Objective:To retrospectively analyzed the risk factors of coronary slow flow(CSF).Method:A total of 307 patients were included,and divided into CSF group(n=183)and control group(n=124).The corrected TIMI frame count(cTFC)was used to diagnose the CSF.Clinical data and biochemical parameters were determined,T-test,Chi-squaretest and Logistic regression analysis was performed.Results:Compared with control group,CSF group had higher rate of smoking and male,higher level of hematocrit,hemoglobin and serum creatinine.Logistic regression analysis revealed that higher hematocrit(O R=1.083,95%CI 1.020-1.150,P=0.009)and male(O R=1.857,95%CI 1.074-3.213,P=0.027)were the independent risk factors for CSF.Spearman analysis showed that male,HCT and HGB were positively related with CSF lesions.Conclusion:Male hormone and higher HCT may be involved in the pathophysiological process of CSF.

关 键 词：冠状动脉慢血流 危险因素 红细胞压积 

分 类 号：R543.3[医药卫生—心血管疾病]