鸭坦布苏病毒江西分离株全基因组序列分析  

Genetic Characteristics of Duck Tembusu Virus Isolated in Jiangxi

作　　者：刘烈发[1] 叶林方[1] 吴浩[1] 黄烨祯 谢玉萍[1] 刘远超 高琳[1] LIU Lie-fa;YE Lin-fang;WU Hao;HUANG Ye-zhen;XIE Yu-ping;Yuan-chao;GAO Lin(Jiangxi Animal Disease Prevention and Control Center,Nanchang,Jiangxi　330029,China)

机构地区：[1]江西省动物疫病预防控制中心,江西南昌330029

出　　处：《福建农业学报》2018年第1期7-11,共5页Fujian Journal of Agricultural Sciences

基　　金：江西省科技计划农业领域重点项目(20151BBF60049)

摘　　要：为了解江西省鸭坦布苏病毒(Duck Tembusu virus,DTMUV)的遗传变异情况,对2013年江西省某蛋鸭场分离获得的1株鸭坦布苏病毒(命名为YF株)进行基因组分子特征及遗传进化分析。序列分析表明,该株病毒基因组全长10 990nt,未出现核苷酸插入或缺失及基因重组的变异情况,与已报道的DTMUV分离株的核苷酸同源性均在98.5%以上,且亲缘关系与当前鸭群中优势病毒亚群非常近。以上结果表明,近年来江西鸭群中流行的鸭坦布苏病毒遗传比较稳定,未发生变异。Genetic characteristics and variation of the epidemic strain of duck Tembusu virus(DTMUV)found in Jiangxi Province were investigated.A DTMUV strain,designated as YF,was isolated from a clinical case in 2013.A sequence analysis showed the viral genome of YF to be 10,990 nt in length with no Ins/Del or genetic recombination.It shared no less than 98.5%homology with the viral strains isolated from ducks since 2010.Phylogenetically,YF had a close relationship with currently circulating dominant virus lineage.It appeared that the DTMUV in local ducks had been genetically stable throughout these years.

关 键 词：鸭坦布苏病毒 YF株 全基因组 序列分析 

分 类 号：S858.32[农业科学—临床兽医学]