迎随补泻法针刺下合穴对胃食管反流病患者反流症状、心理症状及胃动素水平的影响  

Effect of Needling Lower He-sea Points with Directional Reinforcement and Reduction Method on Reflux and Mental Symptoms and Motilin Level in Patients with Gastroesophageal Reflux

作　　者：李赛赛[1] 杨云涛[1] 潘冉[1] 岳岩岩 LI Sai-sai;YANG Yun-tao;PAN Ran;YUE Yan-yan(Third Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China)

机构地区：[1]河南中医药大学第三附属医院,郑州450008

出　　处：《上海针灸杂志》2018年第4期363-368,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：河南省中医药科学研究专项课题(2015ZY02014)

摘　　要：目的观察迎随补泻法针刺下合穴对胃食管反流病患者反流症状、心理症状及胃动素水平的影响。方法收集胃食管反流病患者62例,根据随机数字表分为对照组和观察组,每组31例。对照组给予常规西药治疗,口服奥美拉唑肠溶片,每次20 mg,每日2次;观察组给予迎随补泻法针刺下合穴治疗,取双侧足三里、上巨虚、下巨虚、阳陵泉、委中、委阳,予迎随补泻法,留针30 min,每日1次。两组患者均治疗4周。治疗结束后对比分析两组临床疗效、反流性疾病问卷(RDQ)、心理症状、生活质量、血清胃泌素、血浆胃动素水平以及不良反应发生情况。结果治疗后两组反流症状严重程度、频率以及RDQ总分降低,SAS评分、SDS评分降低,SF-36躯体健康总评分以及SF-36精神健康总评分升高,血清胃泌素及血浆胃动素水平升高,差异具有统计学意义(P<0.05);治疗后与对照组相比,观察组临床总有效率较高,反流症状严重程度、频率以及RDQ总分较低,SAS评分、SDS评分较低,SF-36躯体健康总评分以及SF-36精神健康总评分较高,血清胃泌素及血浆胃动素水平较高,差异具有统计学意义(P<0.05)。两组不良反应相比,无显著差异(P>0.05)。结论迎随补泻法针刺下合穴对胃食管反流病患者能够显著提高临床疗效,改善反流症状、心理症状,调节血浆胃动素含量,从而促进食管下括约肌功能恢复,是一种治疗胃食管反流病的有效方法。Objective To observe the effect of needling lower He-sea points with directional reinforcement and reduction method on reflux and mental symptoms and motilin level in patients with gastroesophageal reflux(GER).Method Sixty-two GER patients were recruited and assigned into a control group and an observation group by the random number table,with 31 cases in each group.The control group was given conventional Western medication,i.e.oral administration of Omeprazole enteric-coated tablets,20 mg each time,twice a day.The observation group was intervened by needling lower He-sea points with directional reinforcement and reduction method.Bilateral Zusanli(ST36),Shangjuxu(ST37),Xiajuxu(ST39),Yanglingquan(GB34),Weizhong(BL40)and Weiyang(BL39)were treated with the directional reinforcement and reduction method,with needles retained for 30 min,and the treatment was given once per day.The intervention lasted for 4 weeks in the two groups.After the treatment,clinical efficacy,Reflux Disease Questionnaire(RDQ),mental symptoms,quality of life,motilin levels in serum and plasma and adverse reactions in the two groups were compared and analyzed.Result After the treatment,in both groups,the severity and frequency of reflux and the total score of RDQ dropped,scores of Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)dropped,the aggregate scores of both physical and mental health in the 36-item Short-form Health Survey(SF-36)increased,and motilin levels in serum and plasma increased,all with a statistical significance(P<0.05).Compared with the control group after the treatment,the total effective rate was higher,the severity and frequency of reflux and total score of RDQ were lower,SAS and SDS scores were lower,the aggregate scores of both physical and mental health in SF-36 were higher,and motilin levels in serum and plasma were higher in the observation group,all with a statistical significance(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Needling lowe

关 键 词：迎随补泻法 针刺疗法 下合穴 胃食管反流 心理疗法 胃动素 

分 类 号：R246.1[医药卫生—针灸推拿学]