色素性毛表皮痣的发病机制及治疗进展  

Research Review of Pathogenesis and Treatment in Becker Nevus

作　　者：刘斯雅 杨斌 LIU Si-ya;YANG Bin(Graduate School of Guangdong Medical University,Zhanjiang 524000,Guangdong,China;Department of Dermatology,Dermatology Hospital of Southern Medical University,Guangzhou 510091,Guangdong,China;Department of Dermatology,Guangdong Province Dermatology Hospital,Guangzhou 510091,Guangdong,China)

机构地区：[1]广东医科大学研究生学院,广东湛江524000 [2]南方医科大学皮肤病医院皮肤科,广东广州510091 [3]广东省皮肤病医院皮肤科,广东广州510091

出　　处：《中国美容医学》2018年第3期149-152,共4页Chinese Journal of Aesthetic Medicine

摘　　要：色素性毛表皮痣是以皮肤褐色斑片伴毛发生长为特点的色素性皮肤病,作为损容性皮肤病的一种,严重影响患者的皮肤外观及心理健康。其发病机制尚不十分明确,既往研究认为可能与雄激素及其受体相关,近年来有学者提出染色体突变和遗传可能也参与了发病。在治疗上主要包括手术切除后植皮、液氮、化学磨削以及近年来提出的光电治疗等,但其复发率高给治疗带来了一定难度。因此,本文就色素性毛表皮痣近年来的研究进展作一综述。Becker nevus is a form of acquired hyperpigmentation predominantly characterized by hairy skin with brown patches.This discosmetic dermatosis severely affects the skin appearance and even the mental health of patients*.Androgens and its receptors are possibly involved in the progression of Becker nevus,but the pathogenesis is not clear yet.Recent studies show that chromosome mutations and inheritance may also play an important role in the disease progression.Surgical removal and skin graft,liquid nitrogen or chemical grinding,and laser treatment are nomally used in the treatment of this disease.However,the high recurrence makes it difficult to be cured.Therefore,in this review,we discussed the research progress published in recent years,and eventually we would be able to provide more information for further research of Becker nevus.

关 键 词：色素性毛表皮痣 BECKER痣 Becker黑变病 Becker痣综合征 

分 类 号：R758.51[医药卫生—皮肤病学与性病学]