扬州45家基层医院质子泵抑制剂合理用药分析  

Analysis on Rational Use of Proton Pump Inhibitors from 45 Grassroots Hospitals in Yangzhou City

作　　者：李全良[1] 夏海建[1] 林郁[1] 黄富宏[1] 焦乾升[1] Li Quanliang;Xia Haijian;Lin Yu;Huang Fuhong;Jiao Qiansheng(The Affiliated Hospital of Yangzhou University,Yangzhou,Jiangsu,China 225009)

机构地区：[1]江苏省扬州市第一人民医院,江苏扬州225009

出　　处：《中国药业》2018年第4期94-96,共3页China Pharmaceuticals

摘　　要：目的为临床合理使用质子泵抑制剂提供参考。方法调取扬州地区45家基层医院2016年3月1日至3月5日使用质子泵抑制剂的处方502张,统计患者年龄、临床诊断、给药途径、不合理联合用药分布情况。结果年龄未超过16岁的患者7例(1.39%),17~59岁160例(31.87%),60岁以上335例(66.73%);符合适应证用药195例(38.84%),无适应证用药127例(25.30%),用药依据不足180例(35.86%);静脉滴注给药303例(59.30%),口服给药210例(41.10%);不合理联用69例(13.75%),其中同瓶联用问题6例(8.70%),非同瓶联用问题61例(88.41%),代谢问题2例(2.90%)。结论该地区基层医院临床质子泵抑制剂不合理使用现象严重,应加强基层医院医师、药师、护师的合理用药知识技能培训,保障患者用药安全。Objective To provide reference for the rational use of proton pump inhibitor(PPl).Methods Totally 502PPIprescriptions were collected from 45 grassroots hospitals in Yangzhou City from March 1st to March 5 th in 2016,theageofthepatients,the clinical diagnosis,the way of administration,the distribution of the irrational combination of drugs were statistically analyzed.Results The age not more than 16 years old were 7 cases(1.39%),17-59 years old were 160 cases(31.87%),not less than 60 years old were 335 cases(66.73%).There were 195 case s(38.84%)with indications,127 cases(25.30%)without indications,180 cases(35.86%)lacked basis of medication.Totally 303 cases(59.30%)were given intravenous drip,210 cases(41.10%)were orally administered,and 69 cases(13.75%)were imieagonably combined.Aliioug them,there were 6 Cases(8.70%)of the compatibility with the same bottle,61 Cases(88.41?fe)of compatibility with non-bottle combined use,and 2 cases(2.90%)of metabolic problems.Conclusion The use of PPI in die grassroots hospitals"was serious irregidaritfes.The tiuining of rational drugustforphysiciana,phar-niaciatain the grassroots hospitals should be strengthened to ensure the safety of drug use of patients.

关 键 词：基层医院 质子泵抑制剂 合理用药 

分 类 号：R969.3[医药卫生—药理学] R975.2[医药卫生—药学]