降钙素原对急性冠脉综合征患者预后判断的临床价值  

Clinical value of procalcitonin in the prognosis of patients with acute coronary syndrome

作　　者：王明伟[1] 陈玉林[1] 杨威凤[1] 张芳[1] 任开涵[1] WANG Mingwei;CHEN Yulin;YANG Weifeng(Department of Cardiology,the Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China)

机构地区：[1]杭州师范大学附属医院心内科,310015

出　　处：《心电与循环》2018年第2期111-113,120,共4页Journal of Electrocardiology and Circulation

基　　金：杭州市科技计划项目(20150733Q24);杭州市科学技术协会科普项目[2015(39);2017(28)]

摘　　要：目的评价降钙素原对于急性冠脉综合征(ACS)预后判断的临床价值。方法 89例ACS患者分为ST段抬高性心肌梗死(STEMI组)33例,非ST段抬高性心肌梗死(NSTEMI组)27例,不稳定型心绞痛(UA组)29例。测定术前、术后24h、术后48h的血降钙素原水平,随访了解患者发生主要心血管不良事件(MACE)。结果术前、术后24h、术后48h降钙素原对自入院后1、3、6个月MACE评价灵敏度及特异度均较差。随访期间共发生MACE 5例(5.61%)。其中心源性猝死1例、急性充血性心力衰竭2例、再发急性心肌梗死1例、急性脑卒中1例。结论降钙素原与ACS患者近期预后无关。Objective To evaluate the clinical value of procalcitonin(PCT)in the prognosis of patients with acute coronary syndrome(ACS).Methods 33 patients with ST-segment elevation myocardial infarction,27 patients with non-ST-segment elevation myocardial infarction and 29 patients with unstable angina were enrolled.PCT levels were measured before,at 24h and 48h after interventional operation,respectively.Major adverse cardiovascular events(MACE)were observed during follow-up.Results The sensitivity and specificity of PCT before and at 24h and 48h after operation were poor for predicting MACE during follow-up 1 month,3 months and 6 months.A total of 5 MACE(5.61%)including one sudden cardiac death,two acute congestive heart failures,one acute myocardial infarction and one acute stroke occurred during the follow-up periods.Conclusion PCT level is not associated with short-term prognosis of patients with ACS.

关 键 词：降钙素原 急性冠脉综合征 主要心血管不良事件 

分 类 号：R541.4[医药卫生—心血管疾病]