雌激素对系统性红斑狼患者病情活动的影响  

Effect of Estrogen on Disease Activity in Patients with Systemic Lupus Erythematosus

作　　者：李改静 刘慧敏[2] 李小兵 LI Gai-jing;LIU Hui-min;LI Xiao-bing(Hebei Engineering University,Medical Institute,Handan,Hebei Province,056000 China;Hebei Engineering University Hospital,Handan,Hebei Province,056000 China)

机构地区：[1]河北工程大学医学院,河北邯郸056000 [2]河北工程大学附属医院,河北邯郸056000

出　　处：《系统医学》2017年第19期164-168,共5页Systems Medicine

摘　　要：系统性红斑狼疮(SLE)是一种引起多系统、多脏器损害的自身免疫性疾病,遗传因素、环境因素、感染因素、雌激素水平、免疫异常等因素均可影响SLE患者病情的发生发展,由于系统性红斑狼疮发病的性别的差异,雌激素水平在SLE发病机制中的作用越来越受到重视。Systemic lupus erythematosus(SLE)is an autoimmune disease with multiple system and multiple organ damage,which can caused by genetic factors,environmental factors,infection factors,hormones,immune abnormalities and other factors.Those elements can affect the occurrence and development and prognosis of patients with SLE.Because of the difference of the incidence of systemic lupus erythematosus in gender,estrogen level is payed more attention to in the pathogenesis of SLE.

关 键 词：红斑狼疮 系统性 雌激素 雄激素 催乳素 免疫细胞 凋亡 

分 类 号：R473.71[医药卫生—护理学]