固相离子交换法制备高效载银分子筛抗菌剂及其抗菌性能  

Preparation of Highly Active Ag-loaded Zeolite Antimicrobial by Solid Phase Ionic Exchange Method and Its Antibacterial Properties

作　　者：李森[1] 王清涛[1] 于华芹 徐会君[2] 杜庆洋[1] LI Sen;WANG Qingtao;YU Huaqin;XU Huijun;DU Qingyang(School of Materials Science and Engineering,Shandong University of Technology,Zibo 255000;School of Chemical Engineering,Shandong University of Technology,Zibo 255000)

机构地区：[1]山东理工大学材料科学与工程学院,淄博255000 [2]山东理工大学化学工程学院,淄博255000

出　　处：《材料导报》2018年第4期539-544,共6页Materials Reports

摘　　要：以小粒径NaA分子筛为载体,硝酸铵和硝酸银为原料,采用固相离子交换法制备载银分子筛抗菌剂。研究AgNO_3的用量、反应温度和反应时间对载银分子筛载银量的影响。分析了载银分子筛的物相和形貌,考察了载银分子筛的抗菌性能、缓释性能及抗变色性能。结果表明,在反应体系n(NH_4A)∶n(AgNO_3)为1∶2,反应温度为400℃,反应时间为4h条件下制备的载银分子筛,其载银量达到(41.35±0.42)%(质量分数),对大肠杆菌(Escherichia coli)的最小抑菌浓度(Minimum inhibitory concentration,MIC)为10.42×10^(-6),杀菌率达到(98.36±0.28)%,抑菌圈直径为15.8 mm;对金黄色葡萄球菌(Staphylococcus aureus)的MIC值为12.50×10^(-6),杀菌率达到(97.43±0.19)%,抑菌圈直径为13.6mm。所制备的载银分子筛具有良好的缓释性能和抗变色性能。The Ag-loaded antibacterial zeolite was prepared by solid phase ionic exchange method with small particle size of NaA zeolite as carrier,NH 4NO 3 and AgNO 3 as raw material.The influence of the AgNO 3 amount,reaction temperature,and reaction time on the amount of silver load in the zeolite were investigated.The phase composition and morphology of Ag-loaded zeolite were characterized.The antibacterial property,sustained-release performance,and anti-tarnish property of Ag-loaded zeolite were studied.The results showed that the Ag-loaded zeolite synthesized under optimum conditions(i.e.,the molar ratio n(NH 4A)∶n(AgNO 3)=1∶2,reaction temperature was 400℃,reaction duration was 4 h)had the minimum inhibitory concentration(MIC)for escherichia coli(10.42×10-6)with the loaded amount of silver of(41.35±0.42)%(mass fraction).The sterilizing rate of Ag-loa-ded zeolite to escherichia coli was(98.36±0.28)%,and the diameter of inhibition zone was 15.8 mm.When applying the Ag-loaded zeolite to staphylococcus aureus,the MIC was 12.50×10-6,the sterilizing rate was(97.43±0.19)%,and diameter of inhibition zone was 13.6 mm.Meanwhile,the Ag-loaded zeolite had good sustained-release performance and anti-tarnish property.

关 键 词：小粒径NaA分子筛 载银分子筛 固相离子交换法 载银量 抗菌性能 缓释性能 抗变色性 

分 类 号：TB321[一般工业技术—材料科学与工程]