51例肝硬化合并门静脉血栓患者的临床分析  

Clinical Analysis of 51 Cases of Liver Cirrhosis Complicated with Portal Vein Thrombosis

作　　者：熊静平[1,2] 纪文静[2] 张跃新[1] XIONG Jing-ping;JI Wen-jing;ZHANG Yue-xin(Infectious Disease Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang,830054 China;Department of Gastroenterology,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang,830063 China)

机构地区：[1]新疆医科大学第一附属医院感染疾病中心,新疆乌鲁木齐830054 [2]新疆医科大学第二附属医院消化科,新疆乌鲁木齐830063

出　　处：《中外医疗》2017年第36期85-87,共3页China & Foreign Medical Treatment

摘　　要：目的分析肝硬化并门静脉血栓(Portal vein thrombosis PVT)的临床特点。方法对新疆医科大学第一附属医院感染疾病中心2015年11月—2017年10月收治的51例肝硬化患者PVT前、后临床资料进行回顾性分析。结果肝硬化PVT后较PVT前D-二聚体[(1.93±1.40)mg/m L vs(1.00±0.75)mg/m L)]、纤维蛋白原降解产物(FDP)(11.63±5.34)μg/m L vs(8.57±4.65)μg/m L)升高,门静脉主干内径宽度(MPV)[(1.30±0.29)mm vs(1.17±0.21)mm]、脾脏厚径[(5.24±1.02)cm vs(4.81±0.93)cm]增宽,血红蛋白(HB)[(100.29±21.15)g/L vs(103.20±23.12)g/L],白蛋白(ALB)[(28.79±5.25)g/L vs(31.72±3.84)g/L)]降低。发热(39.2%vs 21.6%)、腹痛(29.4%vs 9.8%)、食管静脉曲张(90.2%vs 64.7%)比例高;腹水量增多[(4.86±4.22)cm vs(2.11±2.06)cm]。消化道出血(35.3%vs 17.6%)、原发性腹膜炎(43.1%vs 23.5%)等并发症比例高。结论肝硬化PVT后D-二聚体、FDP升高,MPV、脾脏厚径增宽,HB、ALB降低,临床表现、并发症增多。Objective This paper tries to investigate clinical characteristics of PVT in liver cirrhosis.Methods A retrospective analysis was performed in 51 cases of PVT in liver cirrhosis from November 2015 to October 2017 in this hospital.Clinical manifestations,complications,results of laboratory examination and imaging were analyzed.Results In PVT phase,D-dimer[(1.93±1.40)mg/mL,(1.00±0.75)mg/mL],FDP[(11.63±5.34)μg/mL,(8.57±4.65)μg/mL],MPV[(1.30±0.29)mm vs(1.17±0.21)mm],width of spleen[(5.24±1.02)cm vs(4.81±0.93)cm]increased,HB[(100.29±21.15)g/L vs(103.20±23.12)g/L)],ALB[(28.79±5.25)g/L vs(31.72±3.84)g/L]decreased.The number of patients who had fever(39.2%vs 21.6%),abdominal pain(29.4%vs 9.8%),esophageal varices(90.2%vs 64.7%)increased,ascites increased[(4.86±4.22)cm vs(2.11±2.06)cm].The number of patients who had gastrointestinal bleeding(35.3%,17.6%),spontaneous peritonitis(43.1%vs 23.5%)increased.Conclusion D-dimer,FDP,MPV,width of spleen of PVT increased.HB,ALB decreased.PVT can aggravate symptoms and increase complications.

关 键 词：肝硬化 门静脉血栓形成 临床特点 

分 类 号：R5[医药卫生—内科学]