五项肾功能生化检测指标运用在诊断糖尿病肾功能损伤的临床效果评价  

Evaluation on Clinical Effect of Five Renal Function Biochemical Test Indicators in Diagnosis of Diabetes Renal Function Injury

作　　者：卢丽珊[1] LU Li-shan(Department of Clinical Laboratory,Longyan First Hospital,Longyan,Fujian Province,364000 China)

机构地区：[1]福建省龙岩市第一医院检验科,福建龙岩364000

出　　处：《中外医疗》2017年第35期18-20,共3页China & Foreign Medical Treatment

摘　　要：目的研究在糖尿病肾功能损伤诊断中进行尿液标本尿N-乙酰-D-氨基葡萄糖苷酶(NAG)、尿微量白蛋白(MA),血清标本β2-微球蛋白(β2-MG)、胱抑素C(Cys C)、视黄醇结合蛋白(RBP)检测的价值。方法在2016年9月—2017年9月方便选取该院100例糖尿病患者作为观察组,另外选取同期50名健康受检者作为对照组,收集全部研究对象的尿液样本以及血液样本,均进行NAG、β2-MG、Cys C、RBP、MA五项肾功能生化指标检测,分析检测结果。结果相较于对照组,观察组各组的指标水平以及阳性率均明显更高(P<0.05);相较于NA组,MA组以及CP组各项指标水平以及阳性率均明显更高(P<0.05);相较于MA组,CP组各项指标水平以及阳性率均明显更高,CP组NAG、RBP、Cr、β2-MG、BUN、Cys C阳性率分别为51.72%、41.38%、41.38%、48.28%、44.83%、55.17%(P<0.05)。结论五项肾功能生化检测指标运用在糖尿病肾功能损伤诊断中能够帮助临床早期发现糖尿病肾功能损伤,有助于临床尽早实施治疗,改善患者预后。Objective To research the test value of NAG,MA,β2-MG,Cys C in diabetes renal function.Methods 100 cases of diabetes patients in our hospital from September 2016 to September 2017 were convenient selected as the observation group,besides,50 cases of healthy examination people were used as the control group,and the urine samples and blood samples of all patients were collected for NAG,β2-MG,Cys C,RBP,MA test,and the test results were analyzed.Results The levels of various indicators and positive rate in the observation group were obviously higher than those in the control group(P<0.05),and the levels of various indicators and positive rate in the MA group and CP group were obviously higher than those in the NA group(P<0.05),and the levels of various indicators and positive rate in the CP group were obviously higher than those in the MA group,and the positive rates of NAG,RBP,Cr,β2-MG,BUN,Cys C in the CP group were respectively 51.72%,41.38%,41.38%,48.28%,44.83%,55.17%(P<0.05).Conclusion The application of five renal function biochemical test indicators in diagnosis of diabetes renal function injury can help the early discovery of diabetes renal function,which is conducive to early treatment and improvement of prognosis.

关 键 词：糖尿病 肾功能损伤 生化检测指标 诊断 

分 类 号：R5[医药卫生—内科学]