大剂量的芬太尼对接受瑞芬太尼麻醉的腹腔镜手术患者进行预防性镇痛的效果分析  

Analysis of Effect of Large-dose Fentanyl in Laparoscopic Surgery Patients with Remifentanil Anesthesia for Preventive Analgesia

作　　者：史俊武[1] 王俊华[1] 孔垂霖 SHI Jun-wu;WANG Jun-hua;KONG Chui-lin(Department of Anesthesia,Liyang People’s Hospital,Liyang,Jiangsu Province,213300 China)

机构地区：[1]江苏省溧阳市人民医院麻醉科,江苏溧阳213300

出　　处：《中外医疗》2017年第34期106-107,110,共3页China & Foreign Medical Treatment

摘　　要：目的分析大剂量的芬太尼对接受瑞芬太尼麻醉的腹腔镜手术患者进行预防性镇痛的效果。方法方便选择该院自2016年2月—2017年5月收治的120例行腹腔镜治疗的患者,将其随机分为两组,对照组和观察组,每组60例。两组患者麻醉时均给予瑞芬太尼,且均给予预防性镇痛药物,其对照组联用小剂量芬太尼及氟哌利多,观察组联用大剂量芬太尼,对比两组患者麻醉效果。结果观察组拔管、苏醒时间分别为(9.93±3.86)min、(7.42±2.36)min明显短于对照组(17.83±2.87)min、(9.38±1.52)min,相对比差异有统计学意义(P<0.05)。观察组患者的平均疼痛评分为(1.89±0.82)分、明显高于对照组的(3.89±0.76)分,相对比差异有统计学意义(P<0.05)。观察组不良发应发生率为16.67%,对照组为13.33%,两组差异无统计学意义(P>0.05)。结论对接受瑞芬太尼麻醉的腹腔镜手术患者进行预防性镇痛,采用大剂量芬太尼药物,效果较好,值得应用。Objective To analyze the effect of large-dose fentanyl in laparoscopic surgery patients with Remifentanil anesthesia for preventive analgesia.Methods 120 cases of patients treated with laparoscope admitted and treated in our hospital from February 2016 to May 2017 were convenient selected and randomly divided into two groups with 60 cases in each,both groups used fentanyl at anesthesia,(preventive analgesia drugs),the control group used small-dose fentanyl and droperidol,while the observation group used the large-dose fentanyl,and the anesthesia effect of the two groups was compared.Results The tube drawing time and awakening time in the observation group were obviously shorter than those in the control group,(9.93±3.86)min,(7.42±2.36)min vs(17.83±2.87)min,(9.38±1.52)min,the difference was statistically significant(P<0.05),and the average pain score in the observation group was obviously higher than that in the control group,(1.89±0.82)points vs(3.89±0.76)points,and the difference was statistically significant(P<0.05),and the incidence rate of adverse reactions in the observation group and in the control group was respectively 16.67%and 13.33%,and the difference between groups was not statistically significant(P>0.05).Conclusion The effect of large-dose fentanyl in laparoscopic surgery patients with remifentanil anesthesia for preventive analgesia is good,which is worth application.

关 键 词：大剂量芬太尼 瑞芬太尼 腹腔镜手术 预防性镇痛 

分 类 号：R614[医药卫生—麻醉学]