阿替普酶与尿激酶静脉溶栓治疗急性心肌梗死疗效探讨  

The Treatment of Acute Myocardial Infarction With Altipase and Urokinase Intravenous Thrombolysis

作　　者：李英松[1] LI Yingsong(Cardiovascular Medicine Department,Heilongjiang Provincial Nongken Administration General Hospital,Harbin Heilongjiang 150088,China)

机构地区：[1]黑龙江省农垦总局总医院心血管内科,黑龙江哈尔滨150088

出　　处：《中国继续医学教育》2018年第11期127-129,共3页China Continuing Medical Education

摘　　要：目的对阿替普酶与尿激酶静脉溶栓治疗急性心肌梗死的治疗效果进行对比。方法选择本院2016年9月—2017年11月的86例患者,按照随机分配原则,分为观察组、对照组,每组43例,观察组采用小剂量阿替普酶进行治疗,对照组采用尿激酶静脉溶栓治疗方法,对治疗效果进行分析。结果患者临床效果分析中,观察组总有效率为95.35%,对照组总有效率为79.07%,观察组效果明显,数据差异有统计学意义(P<0.05)。两组患者心血管事件中,观察组心血管事件所占比例为23.26%,对照组心血管事件发生所占比例为46.51%。数据差异有统计学意义(P<0.05)。结论通过阿替普酶治疗急性心肌梗死患者,可以明显提高患者的治疗效果,改善患者的生活质量,缓解患者的溶栓情况。Objective To compare the therapeutic effect of altipase and urokinase in the treatment of acute myocardial infarction.Methods 86 patients in our hospital from September 2016 to November 2017 were selected.According to the principle of random distribution,it was divided into the observation group and the control group,with 43 cases in each group.The observation group was treated with a small dose of altipase.The control group was treated with urokinase thrombolytic therapy.The effect of treatment was analyzed.Results The total effective rate of the observation group was 95.35%,and the total effective rate of the control group was 79.07%.The observation group had obvious effect,and the difference was statistically significant(P<0.05).The cardiovascular events in the two groups were 23.26%,compared with 46.51%in the control group.The difference was statistically significant(P<0.05).Conclusion The treatment of acute myocardial infarction patients with altipase,it can obviously improve the treatment effect of the patients,improve the quality of life of the patients and relieve the thrombolytic condition of the patients.

关 键 词：阿替普酶 尿激酶静脉溶栓 急性心肌梗死 疗效分析 

分 类 号：R542[医药卫生—心血管疾病]