酚妥拉明持续湿敷对多巴胺致皮肤发白初期的效果分析  

Effect Analysis of Continuous Wet Dressing of Phentolamine on the Initial-stage Skin Whitening Caused by Dopamine Injection in Neonates

作　　者：朱小丽[1] 黄桂秀 曾新华[1] ZHU Xiao-li;HUANG Gui-xiu;ZENG Xin-hua(The First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000;Yudu People's Hospital,Yudu,Jiangxi 342300)

机构地区：[1]赣南医学院第一附属医院,江西赣州341000 [2]于都县人民医院,江西于都342300

出　　处：《赣南医学院学报》2018年第3期258-259,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：2014年赣州市指导性科技计划项目

摘　　要：目的:比较酚妥拉明和硫酸镁两种药物持续湿敷对多巴胺致患儿皮肤发白初期的效果。方法:选取我院收治的70例休克前期患儿,均接受过多巴胺静脉注射治疗,且出现皮肤发白并发症;随机分为对照组和观察组各35例;对照组硫酸镁持续湿敷,观察组酚妥拉明持续湿敷,比较两组效果。结果:观察组治疗有效率(91.43%)显著高于对照组(65.71%),差异有统计学意义(P<0.05)。结论:酚妥拉明持续湿敷对多巴胺导致患儿皮肤发白初期的治疗效果显著,其能够有效降低外周血管阻力,改善患儿的缺血症状,值得推广应用。Objective:To compare the effects of the continuous wet dressing of phentolamine and magnesium sulfate in treating skin whitening caused by intravenous injection of dopamine;To clarify both of their application value.Method:Seventy cases of preshock children admitted in our hospital and treated with dopamine intravenous injection with the occurrence of skin whitening complications were randomly divided into the control group and the observation group with 35 cases in each group.In the control group,the continuous wet dressing of magnesium sulfate was adopted,while for the observation group,the continuous wet dressing of phentolamine was given;the therapeutic effects of the two groups were compared and analyzed.Results:The effective rate of treatment in the observation group reached 91.43%which was much higher than that of the control group(65.71%).There was statistical difference between this two sets of data.Conclusion:Continuous wet application of phentolamine on the initial-stage skin whitening in neonates can effectively reduce the peripheral vascular resistance and improve the ischemic symptoms of the neonates.It is worth popularizing and applying.

关 键 词：新生儿 多巴胺 酚妥拉明 

分 类 号：R473.72[医药卫生—护理学]