国产BuMA支架与EXCEL支架在急性冠脉综合征患者中的临床应用比较  

Comparison in clinical application between domestic Bu MA stent and EXCEL stent in patients with acute coronary syndrome

作　　者：李雪蛟 张刚[1] 罗军[1] 田攀 曹雪滨[1] 杨丽娟 张龙飞[1] Li Xuejiao;Zhang Gang;Luo Jun;Tian Pan;Cao Xuebin;Yang Lijuan;Zhang Longfei(Department of Cardiology,Chinese PLA 252 Hospital,Baoding 071000,China)

机构地区：[1]中国人民解放军252医院心内科,保定071000

出　　处：《中国循证心血管医学杂志》2018年第3期355-357,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的比较国产Bu MA和EXCEL药物洗脱支架治疗急性冠脉综合征患者的中远期临床疗效和安全性。方法回顾性分析在中国人民解放军252医院治疗的急性冠脉综合征患者346例,其中Bu MA支架组217例,EXCEL支架组129例,观察两组患者的基线临床资料、PCI术后12个月及24个月的支架血栓及主要心脏不良事件的发生率。结果两组患者的基线临床资料差异无统计学意义(P>0.05);PCI术后12个月及24个月的心源性死亡率、非致死性心肌梗死率、靶血管血运重建率、支架内血栓发生率,差异均无统计学意义(P>0.05)。结论国产Bu MA和EXCEL药物洗脱支架,在治疗急性冠脉综合征患者中远期疗效相近,均具有较高的安全性。Objective To compare the mid-long term clinical efficacy and safety between drug eluting stents(DES)of BuMA and EXCEL in patients with acute coronary syndrome(ACS).Methods ACS patients(n=346)were retrospectively analyzed in Chinese PLA 252 Hospital,among them,217 with BuMA stents(BuMA group)and 129 with EXCEL stents(EXCEL group).The clinical baseline materials,and incidence of in-stent thrombosis and cardiac adverse events after PCI for 12 months and 24 months were observed in 2 groups.Results The difference in clinical baseline materials had no statistical significance between 2 groups(P>0.05).The difference in incidence of cardiac death,non-fatal myocardial infarction,target vessel revascularization,in-stent thrombosis had no statistical significance between 2 groups(P>0.05)after PCI for 12 months and 24 months.Conclusion The domestic DES of BuMA is similar to DES of EXCEL in mid-long term clinical efficacy and both of them have higher safety in treatment of ACS patients.

关 键 词：药物洗脱支架 急性冠脉综合征 经皮冠状动脉介入治疗 疗效 

分 类 号：R541.4[医药卫生—心血管疾病]