血浆D-二聚体的检测和血气分析在慢性阻塞性肺疾病中的相关性探讨  

Correlation between Plasma D-dimer and Blood Gas Analysis in Chronic Obstructive Pulmonary Disease

作　　者：殷建云 YIN Jian-yun(Department of Respiration,Pizhou People's Hospital,Xuzhou,Jiangsu Province,221300 China)

机构地区：[1]邳州市人民医院呼吸科,江苏南通221300

出　　处：《中外医疗》2018年第5期37-39,共3页China & Foreign Medical Treatment

摘　　要：目的探讨血浆D-二聚体的检测和血气分析在慢性阻塞性肺疾病(COPD)中的相关性。方法方便选择该院2016年1月—2017年8月治疗的74例慢性阻塞性肺疾病患者,其中37例为急性期,设为观察组,余37例为缓解期,设为对照组,分别抽血检查两组患者血浆D-二聚体和血气分析,比较两组的检查结果。结果观察组患者的D-二聚体明显高于对照组,动脉血氧分压低于对照组,动脉血二氧化碳分压高于对照组,两组在上述等方面差异有统计学意义(P<0.05),观察组D-二聚体、PO2、PCO2分别为(1.72±0.94)mg/L、(61.31±10.54)mm Hg、(59.45±12.11)mm Hg。结论慢性阻塞性肺疾病患者的D-二聚体及血气分析之间关系密切,临床上可通过监测D-二聚体及血气分析变化,对患者血栓性疾病的早期诊断及预后评估有重要临床意义。Objective This paper tries to investigate the correlation between plasma D-dimer and blood gas analysis in chronic obstructive pulmonary disease(COPD).Methods A total of 74 cases with chronic obstructive pulmonary disease admitted to the People's Hospital of Pizhou City from January 2016 to August 2017 were convenient selected as the research objects,and the observation group had 37 cases at acute stage,while the control group consisted of the rest 37 cases of remission.Separate blood tests were performed to examine plasma D-dimer and blood gas analysis in both groups,then the test results were compared.Results D-dimer in observation group was significantly higher than that in control group while the arterial oxygen partial pressure in the control group was higher than that in the observation group,and the arterial partial pressure of carbon dioxide of the observation group was higher than that of the control group.As a result,the differences between the two groups were significant(P<0.05).D-dimer,PO2 and PCO2 in the observation group were(1.72±0.94)mg/L,(61.31±10.54)mmHg and(59.4 5±12.12)mmHg.Conclusion D-dimer and blood gas analysis in patients with chronic obstructive pulmonary disease are closely related,clinically monitoring D-dimer and blood gas analysis changes has important clinical significance in early diagnosis and prognosis of patients with thrombotic disease.

关 键 词：血浆D-二聚体 血气分析 慢性阻塞性肺疾病 

分 类 号：R563[医药卫生—呼吸系统]