急性带状疱疹感染合并2型糖尿病的老年患者降糖治疗对神经性疼痛及住院天数的影响  

Effect of Hypoglycemic Treatment on Neuropathic Pain and Hospital Stay in Elderly Patients with Acute Herpes Zoster Infection and Type 2 Diabetes

作　　者：冯文静[1] 刘虹[1] 张睿[1] FENG Wen-jing;LIU Hong;ZHANG Rui(Department of Geriatric,Leshan People’s Hospital,Leshan,Sichuan Province,614000 China)

机构地区：[1]四川省乐山市人民医院老年病科,四川乐山614000

出　　处：《中外医疗》2018年第1期13-15,19,共4页China & Foreign Medical Treatment

摘　　要：目的评估合并2型糖尿病的急性带状疱疹感染老年患者控制血糖对神经性疼痛及住院日的影响。方法方便选择2013年1月—2015年12月于该院住院治疗的合并2型糖尿病的急性带状疱疹感染老年患者共60例,随机分为3组,各20例,A组予改变生活方式治疗,B组予口服降糖药治疗,C组予胰岛素治疗。根据血糖达标情况分别观察神经性疼痛缓解情况及住院时间。结果血糖控制达标组较不达标组在各观察指标方面均差异有统计学意义(P<0.05),达标组:治疗后疼痛评分(0.64±0.53)分,缓解天数(6.70±2.91)d,住院天数(9.05±2.82)d;未达标组:治疗后疼痛评分(1.09±0.28)分,缓解天数(12.87±2.92)d,住院天数(15.35±3.34)d。止痛药使用种类差异无统计学意义(P=0.093),A组治疗后疼痛评分(1.06±0.24)分,B组治疗后疼痛评分(0.56±0.50)分,C组治疗后疼痛评分(0.60±0.50)分;A组缓解天数(13.12±3.22)d,B组缓解天数(7.50±3.06)d,C组缓解天数(6.20±3.06)d;A组住院天数(14.90±4.06)d,B组住院天数(9.59±3.50)d,C组住院天数(9.00±2.61)d。A、B、C组之间在疼痛评分、疼痛缓解时间及住院天数方面均差异有统计学意义(P<0.05),其中B组、C组较A组均差异有统计学意义(P<0.01),C组较B组在疼痛缓解时间方面差异有统计学意义(P=0.047)。结论控制血糖减轻了急性带状疱疹感染老年2型糖尿患者者的疼痛,并缩短了疼痛缓解时间及住院天数。Objective This paper tries to assessing the effects of glycemic control on neuropathic pain and length of stay in elderly patients with acute herpes zoster infection complicated with type 2 diabetes Methods Convenient selected a total of 60 elderly patients with type 2 diabetes mellitus admitted to this hospital from January 2013 to December 2015 were randomly divided into 3 groups with 20 cases in each.Patients in group A were given life-style treatment,group B to oral hypoglycemic agents,group C to insulin treatment.According to the blood glucose compliance,neurotic pain relief and hospital stay were observed.Results Blood glucose control standard group than the non-compliance group in the observation of indicators were statistically significant different(P<0.05),the standard group:post-treatment pain score(0.64±0.53)points,(6.70±2.91)d relief,hospitalization days(9.05±2.82)d;non-standard group:post-treatment pain score(1.09±0.28)points,days of remission(12.87±2.92)d,days of hospitalization(15.35±3.34)d.There was no significant difference in the types of analgesics(P=0.093).The pain score of group A was(1.06±0.24)points,the pain score of group B was(0.56±0.50)points,the pain score of group C was(0.60±0.50)points,and the number of days of remission of group A was(13.12±3.22)d,the number of days in group B was(7.50±3.06)d,the number of days in group C was(6.20±3.06)d;the number of days in group A was(14.90±4.06)d,the number of days in group B was(9.59±3.50)d,and the length of stay in group C was(9.00±2.61)d.There were significant differences in pain score,pain relief time and length of hospital stay between groups A,B and C(P<0.05),and the difference was statistically significant(P<0.01)between the B、Cgroup and A group,difference was statistically significant in the C group than B group in pain relief time(P=0.047).Conclusion Controlling blood glucose relieves the pain associated with acute shingles infection in elderly type 2 diabetes and shortens pain relief and hospital stays.

关 键 词：带状疱疹 老年2型糖尿患者者 神经性疼痛 住院天数 

分 类 号：R58[医药卫生—内分泌]