脱水剂在急性脊髓损伤中的应用进展  

Application Progress of Dehydrating Agent in Acute Spinal Cord Injury(review)

作　　者：张超[1,2,3,4] 李建军 杨德刚[1,2,3,4] 杨明亮 杜良杰[1,2,3,4] 张文豪 刘长彬[1,2,3,4] 李大鹏 胡安明[1,5] 秦川 ZHANG Chao;LI Jian-jun;YANG De-gang;YANG Ming-liang;DU Liang-jie;ZHANG Wen-hao;LIU Chang-bin;LI Da-peng;HU An-ming;QIN Chuan(Capital Medical University School of Rehabilitation Medicine,Beijing 100068,China;Department of Spinal and Neural Function Reconstruction,Beijing Bo'ai Hospital,China Rehabilitation Research Center,Beijing 100068,China;Center of Neural Injury and Repair,Beijing Institute for Brain Disorders,Beijing 100068,China;Center of Neural Injury and Repair,Beijing Institute for Brain Disorders,Beijing 100068,China;Beijing Key Laboratory of Neural Injury and Rehabilitation,Beijing 100068,China)

机构地区：[1]首都医科大学康复医学院,北京市100068 [2]中国康复研究中心北京博爱医院脊柱脊髓神经功能重建科,北京市100068 [3]北京脑重大疾病研究院神经损伤与修复研究所,北京市100068 [4]北京市神经损伤与康复重点实验室,北京市100068 [5]中国康复研究中心北京博爱医院神经外科,北京市100068

出　　处：《中国康复理论与实践》2018年第4期373-377,共5页Chinese Journal of Rehabilitation Theory and Practice

基　　金：中央级公益性科研院所基本科研业务费专项资金项目(No.2016CZ-4);中国康复研究中心课题(No.2012-1;No.2013-7)~~

摘　　要：急性脊髓损伤(ASCI)可分为原发性损伤和继发性损伤。脊髓水肿对脊髓继发性损伤的发展至关重要。脊髓水肿主要分为细胞毒性水肿和血管源性水肿。脱水剂在ASCI后水肿的治疗中作用明显。本文主要介绍甘露醇、高渗盐水、甘油果糖、呋塞米、人血白蛋白、白藜芦醇等脱水剂在ASCI治疗中的应用进展。Acute spinal cord injury(ASCI)can be divided into primary injury and secondary injury.Spinal cord edema is important for the development of secondary injury after ASCI.Spinal cord edema can be mainly divided into cytotoxic edema and angioedema.The application of dehydrating agents in the treatment of acute spinal cord injury is obvious.This article described the application of mannitol,hypertonic saline,glycerol fructose,furosemide,human serum albumin,resveratrol and other dehydrating agents in the treatment of ASCI.

关 键 词：脊髓损伤 水肿 脱水剂 综述 

分 类 号：R651.2[医药卫生—外科学]