强化阿托伐他汀治疗对冠心病患者PCI术后影响分析  

Effect of Atorvastatin on Inflammatory Factors and Renal Function After Percutaneous Coronary Intervention in Patients With Coronary Heart Disease

作　　者：孔丽丽[1] KONG Lili(Department of Clinical Medicine,Binzhou Medical School,Yantai Shandong 264003,China)

机构地区：[1]滨州医学院临床医学系心内科,山东烟台264003

出　　处：《中国卫生标准管理》2018年第7期74-75,共2页China Health Standard Management

摘　　要：目的分析经皮冠状动脉介入治疗的冠心病患者采用强化阿托伐他汀治疗的临床效果。方法选择50例2016年1月—2017年10月收治的冠心病介入治疗患者,分为对照组和研究组,各25例,分别给予常规剂量和强化阿托伐他汀治疗,观察两组治疗效果。结果研究组术后CRP、IL-和TNF-α均低于对照组,差异有统计学意义(P<0.05),研究组术后Bun、Cys-C结果低于对照组,Ccr和e GFR均高于对照组,差异有统计学意义(P<0.05)。结论强化阿托伐他汀治疗可有效降低冠心病介入治疗患者的炎性因子,改善患者肾功能,可加强应用。Objective To analyze the clinical effect of intensive atorvastatin in patients with coronary artery disease treated by percutaneous coronary intervention.Methods 50 patients with coronary heart disease received interventional treatment from January 2016 to October 2017 were divided into control group and study group,25 cases in each group.They were given routine dose and intensive atorvastatin treatment respectively,and the therapeutic effects of two groups were observed.Results The postoperative CRP,IL-and TNF-alpha in the study group were significantly lower than those in the control group(P<0.05).The Bun and Cys-C results in the study group were significantly lower than those in the control group,Ccr and eGFR were significantly higher than those in the control group,with a statistically significant difference(P<0.05).Conclusion The treatment of atorvastatin can effectively reduce the inflammatory factors and improve the renal function of patients with coronary heart disease,and it can be applied.

关 键 词：阿托伐他汀 炎性因子 经皮冠状动脉介入 肾功能 治疗效果 

分 类 号：R972[医药卫生—药品]