光-温度双重响应PNIPAM-b-PPAPEA共聚物的合成及其胶束特性  

Synthesis and micellar behavior of photo-temperature dual responsive PNIPAM-b-PPAPEA copolymers

作　　者：黄成进 王敏 冯乙 李光华 朱园勤 赖刚 HUANG Cheng-jin;WANG Min;FENG Yi;LI Gang-hua;ZHU Yuan-qin;LAI Gang(Guangxi Key Laboratory of Petrochemical Resource Processing&Process Intensification Technology,School of Chemistry and Chemical Engineering,Guangxi University,Nanning 530004,China)

机构地区：[1]广西大学化学化工学院,广西石化资源加工及过程强化技术重点实验室,广西南宁530004

出　　处：《化学研究与应用》2018年第4期550-556,共7页Chemical Research and Application

基　　金：国家自然科学基金项目(21064001)资助;广西自然科学基金项目(2014GXNSFAA118042)资助

摘　　要：本文以二硫代苯甲酸异丁腈酯(CPDB)作为链转移剂,AIBN为引发剂,以N-异丙基丙烯酰胺(NIPAM)和2-(4-苯基偶氮苯氧基)乙基丙烯酸酯(PAPEA)为单体,利用RAFT聚合法合成了PNIPAM及其嵌段共聚物PNIPAM-b-PPAPEA。利用FT-IR、~1H NMR、GPC对PNIPAM及其嵌段共聚物的结构进行了表征。同时,通过TEM、DLS和UV等手段测定了该嵌段共聚物胶束的形貌及大小、胶束的光响应性和温度响应性。结果表明,PAPEA的RAFT聚合反应动力学曲线呈良好的线性关系,PNIPAM-b-PPAPEA分子量分布小于1.3;PNIPAM-b-PPAPEA在水相中自组装形成球形胶束,其粒径随PPAPEA链段分子量的增加而增大;胶束呈现出良好的光响应性;随着温度的升高,胶束粒径变小,显示出明显的温度响应性。In this paper,poly(N-isopropyl acrylamide)(PNIPAM)and its block copolymer poly(N-isopropyl acrylamide)-b-poly[2-(4-phenylazophenoxy)ethyl acrylate](PNIPAM-b-PPAPEA)were synthesized by the RAFT polymerization of NIPAM and PAPEA,using 2-cyanoprop-2-yl dithiobenzoate(CPDB)as a chain transfer agent and AIBN as initiator.The structure of PNIPAM and its block copolymerswascharacterized by FT-IR,1H-NMR,and GPC.And,the morphology and size of block copolymer micelles,photo-and thermo-responsiveness were determined by TEM,DLS,and UV.The results showed that the kinetic curve of RAFT polymerization of PAPEA reveals good linear relationship,and the molecular weight distributions of PNIPAM-b-PPAPEAwas less than 1.3;PNIPAM-b-PPAPEA in aqueous phase formed spherical micelles via self-assembly and the micelles size was increased with the increasing of the molecular weight of PPAPEA block;the micelles exhibited good photo-responsiveness;the micelles size became smaller with the temperature increased,which indicated that the micelles show obvious thermo-responsiveness.

关 键 词：NIPAM 2-(4-苯基偶氮苯氧基)乙基丙烯酸酯 RAFT聚合 嵌段共聚物 胶束 刺激响应性 

分 类 号：O631.2[理学—高分子化学]