幽门螺杆菌感染与血液系统疾病的关系  

Relationship between Helicobacter pylori infection and hematologic system diseases

作　　者：王雪[1] 赵心怡 吕晓辉[1] 李异玲[1] WANG Xue;ZHAO Xinyi;LYU Xiaohui;LI Yiling(Department of Gastroenterology,the First Affiliated Hospital of China Medical University,Shenyang 110000,China)

机构地区：[1]中国医科大学附属第一医院消化内科,辽宁沈阳110000

出　　处：《胃肠病学和肝病学杂志》2018年第2期134-137,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：幽门螺杆菌(Helicobacter pylori,H.pylori)在全球的感染率超过50%,是人类最常见的感染。除慢性胃炎、胃溃疡、十二指肠溃疡、胃癌等消化系统疾病外,血液系统疾病也被证实与H.pylori相关,包括缺铁性贫血、特发性血小板减少性紫癜、维生素B12缺乏症和黏膜相关组织淋巴瘤。以上血液疾病患者的H.pylori感染率均比正常人高,且进行H.pylori根除治疗后症状都得到不同程度的缓解。H.pylori直接或间接地通过不同机制影响或决定着4种血液系统疾病的发生。Helicobacter pylori(H.pylori)is infected more than 50%in the world,making it the more common infection in humans.In addition to digestive diseases such as chronic gastritis,gastric ulcer,duodenal ulcer and gastric cancer,blood system diseases have also been proven to be associated with H.pylori,including iron deficiency anemia(IDA),idiopathic thrombocytopenic purpura(ITP),vitamin B12 deficiency and mucosa-associated lymphoid tissue(MALT)lymphoma.The H.pylori infection rate of the four kinds of blood system diseases patients is higher than normal person and the symptoms will be alleviated after H.pylori eradication therapy.H.pylori affects or determines the occurrence of these blood system diseases directly or indirectly through the different mechanisms.

关 键 词：幽门螺杆菌 缺铁性贫血 特发性血小板减少性紫癜 维生素B12缺乏症 黏膜相关组织淋巴瘤 

分 类 号：R378[医药卫生—病原生物学]