NLR LMR与冠心病相关性的研究  

The Study on the Correlation between NLR LMR and Coronary Heart Disease

作　　者：严亚琪 李硕 董文超[1] 刘超[1] 丁振江[1] 王瑞鹃[1] YAN Yaqi;LI Shuo;DONG Wenchao(The Affiliated Hospital of Chengde Medical University,Hebei Chengde 067000,China)

机构地区：[1]承德医学院附属医院心脏内科,河北承德067000

出　　处：《河北医学》2018年第4期612-615,共4页Hebei Medicine

摘　　要：目的:探讨患者外周血中性粒细胞/淋巴细胞(NLR)、淋巴细胞/单核细胞(LMR)的比值与冠心病的关系。方法:连续入选于我院住院的可疑冠心病患者86例,根据造影结果将入选者分为冠心病组(54例)和对照组(32例)。收集入选患者基线资料及临床实验室检查资料,计算NLR、LMR,分析其与冠心病的关系。结果:冠心病组患者的NLR高于对照组,LMR低于对照组,差异均有统计学意义(P<0.05)。Spearman相关分析表明NLR与冠心病呈正相关,r=0.287、P=0.007,LMR与冠心病呈负相关,r=-0.219、P=0.043。结论:外周血NLR、LMR与冠心病相关。Objective:To investigate the relationship between peripheral blood neutrophil/lymphocyte ratio(NLR)and lymphocyte/monocyte ratio(LMR)and coronary heart disease.Method:A total of 86 patients who are suspected as coronary heart disease(CHD)were recruited in this study.According to the results of coronary angiography(CAG),they were divided into CHD group(54 subjects)and control group(32 subjects),respectively.The baseline data and clinical laboratory data were collected.In terms of aboved data,NLR and LMR were calculated and the association between NLR and LMR and coronary heart disease were analyzed.Results:CHD group,compared to control group,had higher NLR and lower LMR(P<0.05);Spearman correlation analysis showed that NLR was positively correlated with CHD,r=0.272,P=0.011;LMR was negatively correlated with CHD,r=-0.219,P=0.043.Conclusions:NLR and LMR in peripheral blood were associated with coronary heart disease.

关 键 词：冠心病 中性粒细胞计数/淋巴细胞计数 淋巴细胞计数/单核细胞计数 

分 类 号：R541.4[医药卫生—心血管疾病]