加味沙参麦冬汤联合孟鲁司特钠对咳嗽变异性哮喘的治疗效果  

Clinical efficacy of the Shashen Maidong decoction plus montelukast sodium on cough variant asthma

作　　者：陆伟恒[1] 

机构地区：[1]广州市黄埔区中医院,广东广州510700

出　　处：《中医临床研究》2018年第8期17-19,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨加味沙参麦冬汤联合孟鲁司特钠对咳嗽变异性哮喘的治疗效果。方法:按照随机数字表法将144例咳嗽变异性哮喘患者分为观察组和对照组各72例,对照组患者给予孟鲁司特钠治疗,观察组患者在此基础上给予加味沙参麦冬汤,比较两组患者中医证候疗效、恢复情况以及治疗前后呼气峰流量变异率、IL-6及TNF-α检测结果。结果:观察组中医证候疗效显著优于对照组,差异有统计学意义(P<0.05);观察组患者症状体征平均缓解时间、症状体征平均消失时间、平均住院时间均显著低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后呼气峰流量变异率、IL-6及TNF-α水平均显著低于对照组,差异有统计学意义(P<0.05)。结论:加味沙参麦冬汤联合孟鲁司特钠治疗咳嗽变异性哮喘疗效显著,可有效改善患者临床症状和炎症因子,缩短康复时间。Objective:To investigate the effect of the Shashen Maidong decoction(沙参麦冬汤)with montelukast sodium on cough variant asthma.Methods:According to random number table method,144 patients were divided into the observation group and control group,72 cases in each group.The control group was given montelukast sodium.The observation group was given the Shashen Maidong decoction.Results:The effect of TCM syndromes in observation group was significantly better than that in the control group(P<0.05).The mean relief time of symptoms and signs,the average disappearance time of symptoms and signs and the average length of stay in the observation group were significantly shorter than those in the control group(P<0.05).The variation of expiratory peak flow rate,IL-6 and TNF-αlevels in the observation group were significantly lower than those in the control group after treatment(P<0.05).Conclusions:The Shashen Maidong decoction with montelukast sodium was effective on cough variant asthma,can effectively improve the clinical symptoms and inflammatory factors and shorten the recovery time.

关 键 词：咳嗽变异性哮喘 加味沙参麦冬汤 孟鲁司特钠 

分 类 号：R256.12[医药卫生—中医内科学]