针刀与局部封闭法治疗肩周炎患者的疼痛介质及炎性因子影响的研究  

A study on the effect of needle knife and partial closure method on pain medium and inflammatory factors in patients with scapulohumeral periarthritis

作　　者：张增富[1] 

机构地区：[1]四川省攀枝花市第四人民医院,四川攀枝花617061

出　　处：《中医临床研究》2018年第8期82-84,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察针刀与局部封闭法对治疗肩周炎患者的疼痛介质和炎性因子水平变化的影响研究。方法:回顾性选取于2014年2月-2017年4月在医院骨伤科接受治疗的76例肩周炎患者为研究对象,根据治疗方式不同分为观察组与对照组,其中观察组的41例患者采用针刀治疗,对照组的35例患者采用局部封闭治疗,在治疗14d后比较两组患者的疼痛介质血清5-羟色胺(5-HT)、前列腺素E2(PGE2)和炎性因子白细胞介素6(IL-6)、肿瘤坏死因子-α(TNF-α)的水平变化。结果:(1)在治疗14d后,观察组患者的IL-6(41.27±5.38)pg/ml和TNF-α(13.52±1.64)pg/ml水平均明显低于对照组的IL-6(56.07±6.79)pg/ml、TNF-α(19.84±1.57)pg/ml(P均<0.05);(2)观察组患者的5-HT(0.29±0.01)μmol/L、PGE2(13.26±1.17)μg/L表达水平也低于对照组患者的5-HT(0.52±0.05)μmol/L、PGE2(25.04±1.83)μg/L水平(P均<0.05)。结论:肩周炎患者采用针刀治疗比局部封闭治疗更能有效降低患者的疼痛介质和炎性因子水平,具有显著的镇痛效果,并对减少机体应激反应有积极的影响。Objective:To observe the effect of needle knife and partial closure method on pain medium and inflammatory factors in patients with scapulohumeral periarthritis.Methods:76 patients were divided into the observation group and the control group.41 patients in the observation group were treated by needles,and 35 patients in the control group were treated by partial closure method.Results:After 14 days,the levels of IL-6 was(41.27±5.38)pg/ml and TNF-αwas(13.52±1.64)pg/ml in the observation group,and significantly lower than(56.07±6.79)pg/ml and(19.84±1.57)pg/ml(P<0.05)in the control group.The expression levels of 5-HT(0.29±0.01)μmol/L and PGE2(13.26±1.17)μg/L in the observation group was also lower than 5-HT(0.52±0.05)μmol/L,PGE2(25.04±1.83)μg/L levels in the control group(P<0.05).Conclusion:Needle knife and partial closure method on scapulohumeral periarthritis is more effective,by reducing the level of pain medium and inflammatory factors.

关 键 词：针刀 局部封闭 肩周炎 疼痛介质 炎性因子 

分 类 号：R323.42[医药卫生—人体解剖和组织胚胎学]