基于萘酰亚胺的Hg^(2+)及Cu^(2+)荧光探针  

Naphthalimide-based Fluorescent Probe for the Detection of Hg^(2+) and Cu^(2+)

作　　者：袁石状 王璐 张天悦 王恩举[1] YUAN Shizhuang;WANG Lu;ZHANG Tianyue;WANG Enju(School of Chemistry and Chemical Engineering,Hainan Normal University,Haikou 571158,China)

机构地区：[1]海南师范大学化学与化工学院,海南海口571158

出　　处：《海南师范大学学报（自然科学版）》2018年第1期13-17,22,共6页Journal of Hainan Normal University（Natural Science）

基　　金：大学生创新训练计划项目(cxcyxj2017011);海南省自然科学基金项目(20162028)

摘　　要：通过衍生化1,8-萘二甲酰亚胺合成了一个含有双磺酰胺基的荧光探针:4-(2-双(对甲基苯磺酰胺基乙基)氨基)乙胺基-N-丁基-1,8-萘二甲酰亚胺(NDS),实现了对汞离子及铜离子的双重识别.在乙醇溶液中,NDS显示淡绿色弱荧光,加入汞离子使荧光变为青色并显著增强,而铜离子引起NDS荧光显著减弱.其它常见金属离子对这两种离子的检测几乎没有影响,铜离子虽然能猝灭NDS荧光,但不会影响NDS对汞离子的荧光增强响应.质谱分析表明,NDS与汞离子及铜离子都形成1∶1的配合物,配合物中磺酰胺基电离失去了氢离子,这在选择性络合汞离子及铜离子过程中起关键作用.A novel fluorescent probe(NDS)based on 1,8-naphthalimide with di-sulfamine groups as binding sites is de-veloped for the detection of Hg2+and Cu2+.In ethanol solution,NDS exhibits highly selective fluorescent turn-on re-sponse for Hg2+and fluorescent turn-off response for Cu2+.Other metal ions including heavy and transition metal ions have no effect on the detection of Hg2+and Cu2+.Cu2+can quench the fluorescence of NDS,but it cannot affect the Hg2+-induced fluorescence.ESI-MS analysis indicates a 1:1 stoichiometry for the complexes between NDS and Cu2+/Hg2+.The sulfamide releases a hydrogen ion that is crucial for the coordination between NDS and Cu2+/Hg2+.

关 键 词：荧光探针 萘酰亚胺 汞离子 铜离子 

分 类 号：O661.1[理学—分析化学]