首次卒中患者卒中后抑郁程度与临床预后关系的探究  

Research on the relationship between post-stroke depression and clinical prognosis in patients with first-onset stroke patients

作　　者：曹孝荣 郭旭[2] 楼亦文 CAO Xiaorong;GUO Xu;LOU Yiwen(The Second Hospital in Yinzhou District of Zhejiang Ningbo,Zhejiang 315912,China;The Second Hospital of Ningbo,Zhejiang 315000,China)

机构地区：[1]宁波市鄞州区第二医院,浙江宁波315912 [2]宁波市第二医院,浙江宁波315000

出　　处：《浙江医学教育》2018年第2期54-56,62,共4页Zhejiang Medical Education

基　　金：宁波市科技项目(编号:2013C50024)

摘　　要：目的:评估首次缺血性卒中患者,卒中后抑郁程度与临床预后的关系。方法:对符合纳入标准的221例首次卒中患者,分别用BDI-Ⅱ、MRS、BBS评估患者的抑郁程度、肢体功能、平衡功能。结果:轻度抑郁患者发生预后不良54例(62.8%),而中重度抑郁患者发生预后不良32例(84.2%)。2组患者次要临床结局比较(Z=11.907,P=0.003)差异有统计学意义,轻度抑郁患者平衡良好29例(56.9%),而中重度抑郁患者平衡良好12例(48.0%)。结论:卒中后抑郁与预后有关,临床医生应该重视卒中后抑郁,在早期做好正确评估、干预,改善卒中后抑郁患者的预后。[Objective]To assess the relationship between post-stroke depression and clinical outcome in first-ever stroke patients.[Method]From March 2013 to February 2016,a total of 221 stroke patients met the criteria from the Yinzhou Second Hospital in Ningbo,BDI-I,MRS and BBS were used to evaluate the degree of depression,limb function and balance function.[Result]Mild depression occurred in 54 patients(62.8%)with poor prognosis,and 32 cases(84.2%)suffered from moderate or severe depression.The secondary clinical outcomes of the two groups were statistically different(Z=11.907,P=0.003),Mild depression was well balanced in 29 patients(56.9%),while moderate or severe depression was well balanced in 12 patients(48%).[Conclusion]Our findings demonstrate the potential relationship between post-stroke depression and clinical outcomes and clinicians should carefully evaluate depressive symptoms in patients with stroke during routine clinical practice.Adequately-powered and well-controlled further studies are necessary to confirm and fully characterize this relationship.

关 键 词：缺血性卒中 卒中后抑郁 临床预后 步态平衡 

分 类 号：R493[医药卫生—康复医学]