小儿流感用抗病毒合剂联合奥司他韦方案的效果  

The Effect of Influenza With Antiviral Mixture Combined With Oseltamivir Solution

作　　者：柏蕾 BO Lei(Department of Pediatrics,Xiangyang Hospital of Traditional Chinese Medicine,Xiangyang Hubei 441000,China)

机构地区：[1]湖北省襄阳市中医医院儿科,湖北襄阳441000

出　　处：《中国继续医学教育》2018年第13期94-95,共2页China Continuing Medical Education

摘　　要：目的探讨给予抗病毒合剂治疗小儿流感对患儿神经功能康复的作用。方法选取2015年5月—2017年2月我院收治的88例小儿流感患儿作为研究对象,并采用随机数字表法分组。对照组给予药物奥司他韦治疗,联合治疗组在对照组基础上,进行给予抗病毒合剂治疗。比较两组症状改善率;治疗方案副作用;干预前后患儿咽痛、咳嗽、鼻塞、流涕、肌肉疼痛症状积分。结果联合治疗组症状改善率高于对照组,差异具有统计学意义(P<0.05);联合治疗组治疗方案副作用和对照组对比,差异无统计学意义(P>0.05),其中,对照组在用药之后有4例患儿发生恶心,有2例出现呕吐,有3例出现腹痛腹泻。联合治疗组有3例患儿发生恶心,有2例出现呕吐,有3例出现腹痛腹泻,有1例出现头痛。干预前,两组咽痛、咳嗽、鼻塞、流涕、肌肉疼痛症状积分对比,差异无统计学意义(P>0.05);干预后,联合治疗组咽痛、咳嗽、鼻塞、流涕、肌肉疼痛症状积分优于对照组,差异具有统计学意义(P<0.05)。结论小儿流感应用抗病毒合剂联合奥司他韦方案的效果确切,安全性高,可有效改善临床症状,无明显不良反应。Objective To study the given antiviral treatment of pediatric flu mixture effect on neural function rehabilitation of children.Methods 88 children with influenza in our hospital from May 2015 to February 2017 were selected as the research subjects.Random number table method was used to group.The control group was given drug oseltamivir treatment,The combined treatment group was given antiviral mixture on the basis of the control group.The improvement rate of symptoms,the side effects of the treatment group,the scores of pharyngeal pain,cough,nasal congestion,runny nose and muscle pain were compared between the two groups.Results The symptom improvement rate in the combined treatment group was higher than that in the control group(P<0.05).There was no significant difference in the side effects between the combined treatment group and the control group(P>0.05).Among them,4 cases of children in the control group had nausea,2 cases had vomiting and 3 cases had abdominal pain and diarrhea.In the combined treatment group,3 cases had nausea,2 cases had vomiting,3 cases had abdominal pain and diarrhea,and 1 case had headache.Before intervention,there was no significant difference in the scores of pharyngeal pain,cough,nasal congestion,runny nose and muscle pain between the two groups(P>0.05).After the intervention,the scores of pharyngeal pain,cough,nasal congestion,runny nose and muscle pain in the combined treatment group were better than those in the control group,the difference was statistically significant(P<0.05).Conclusion Children with influenza antiviral agent application combined oseltamivir scheme,the effect of the precise,high safety,can effectively improve the clinical symptoms,no significant adverse reactions.

关 键 词：抗病毒合剂 奥司他韦 小儿流感 康复 作用 

分 类 号：R725[医药卫生—儿科]