双源CT心肌灌注检测在冠状动脉临界病变的临床应用价值  

Clinical Application Value of Dual-source CT Myocardial Perfusion Test in Coronary Intermediate Lesions

作　　者：高立[1] 袁旭春[1] 胡国迎 聂伟霞 廖文凌[1] GAO LI;YUAN Xu-chun;HU Guo-ying(Department of Radiology,Sun yetsen Cardiovascular Hospital,Shenzhen 518112,Guangdong Province,China)

机构地区：[1]深圳市孙逸仙心血管医院放射科,广东深圳518112

出　　处：《中国CT和MRI杂志》2018年第4期73-76,共4页Chinese Journal of CT and MRI

基　　金：深圳市科创委资助项目;项目编号:JCYJ201504 02094341900

摘　　要：目的探讨双源CT心肌灌注检测评价冠状动脉临界病变的临床价值。方法搜集33例(共41个冠状动脉病变)双源CT冠状动脉成像诊断为临界病变的患者,所有患者均于一周内经冠状动脉造影证实,并行血流储备分数(FFR)检测。将41个冠状动脉临界病变按FFR检测值分为FFR<0.80组和FFR≥0.80组;按照标准A(两个或以上节段心肌灌注异常)、B(一个或以上节段心肌灌注异常)进行心肌灌注分析。结果FFR<0.80和FFR≥0.80两组间心肌灌注检测A、B标准均有统计学差异(标准A:χ2=11.303,P=0.001;标准B:χ2=12.812,P=0.000);应用ROC曲线分析显示心肌灌注检测标准A和标准B对心肌灌注检测均有统计学意义(AUCA=0.734,P=0.017;AUCB=0.798,P=0.002),采用标准B诊断效能较高。结论心肌灌注检测有助于双源CT"一站式"评价冠状动脉临界病变。Objective To study the the clinical value of dual-source CT myocardial perfusion test in the evaluation of cononary intermediate lesions.Methods 33 cases(41 sites)of coronary intermediate lesions underwent dual-source CT coronary angiography and were confirmed by conventional coronary angiography and Fractional Flow Reserve(FFR)test within one week.According to FFR value,41 intermediate lesions were divided into two groups:FFR<0.80 group and FFR≥0.80 group.Dual-source CT myocardial perfusion test of all the cases was performed according to the standard A(≥2 segments myocardium involved)and standard B(≥1 segment myocardium involved).Results There were statistically significant differences in dual-source CT myocardial perfusion between two groups with standard A(χ2=11.303,P=0.001)and standard B(χ2=12.812,P=0.000).ROC curve analysis indicated that both criteria(standard A and standard B)were statistically significant for myocardial perfusion test(AUCA=0.734,P=0.017,AUCB=0.798,P=0.002)and standard B had higher diagnostic efficacy.Conclusion Myocardial perfusion test could be helpful for Dual-source CT in"one-stop"evaluation of coronary intermediate lesions.[Key words]Coronary Intermediate Lesions

关 键 词：冠状动脉临界病变 血流储备分数 心肌灌注 双源CT 

分 类 号：R542.2[医药卫生—心血管疾病]