双源CT与冠状动脉造影对照评价冠状动脉临界病变  

Cinical Significance of Dual-source CT in the Evaluation of Coronary Intermediate Lesions Comparing with Coronary Angiography

作　　者：高立[1] 袁旭春[1] 聂伟霞 刘晓景 胡国栋 陈琴[1] GAO LI;YUAN Xu-chun;NIE Wei-xia(Department of Radiology,Sun yet-sen Cardiovascular Hospital,Shenzhen 518112,Guangdong Province,China)

机构地区：[1]深圳市孙逸仙心血管医院放射科,广东深圳518112

出　　处：《中国CT和MRI杂志》2018年第3期53-55,59,共4页Chinese Journal of CT and MRI

基　　金：深圳市科创委资助项目;项目编号:JCYJ201504020 94341900

摘　　要：目的探讨双源CT冠状动脉成像对于评价冠状动脉临界病变的临床价值。方法搜集33例(共41个冠状动脉病变)行双源CT冠状动脉成像诊断为临界病变的患者,所有患者均于一周内经冠状动脉造影证实,并行血流储备分数(FFR)检测。将41个冠状动脉临界病变按FFR检测值分为FFR?0.80组和FFR≥0.80组;分析双源CT冠状动脉成像两组间斑块负荷和血管重构指数的差异,及其与FFR检测值的相关性。结果 FFR<0.80组与FFR≥0.80组血管重构指数有明显统计学差异(F=16.45,P<0.05),两组间斑块负荷无明显统计学差异(F=0.53,P>0.05),FFR与RI之间显著正相关(r=0.502,P>0.05)。结论双源CT冠状动脉成像评价临界病变血管重构可能提示血流动力学变化。应用双源CT冠状动脉成像评价冠状动脉临界病变有助于临床制定治疗决策。Objective To investigate the clinical value of dual-source CT in the evaluation of cononary intermediate lesion.Methods 33 cases(41 sites)of coronary intermediate lesions underwent dual-source CT coronary angiography and were confirmed by conventional coronary angiography and Fractional Flow Reserve(FFR)test within one week.According to FFR value,41 intermediate lesions were divided into two groups:FFR<0.80 group and FFR≥0.80 group.The differences between two groups in plaque burden and vascular remodeling index and the correlation of those parameters with FFR value were analyzed.Results There was statistically significant difference in vascular remolding index between two groups(F=16.45,P<0.05).There was no statistically significant difference in plaque burden between two groups(F=0.53,P>0.05).There was a significant positive correlation between FFR value and RI(r=0.502,P>0.05).Conclusion Dual-source CT coronary angiography may suggest hemodynamic changes of intermediate lesion by evaluating vascular remodeling,and could be helpful in clinical decision-making.

关 键 词：冠状动脉临界病变 血流储备分数 斑块负荷 

分 类 号：R543.32[医药卫生—心血管疾病]