循环微粒参与动脉粥样硬化进程的机制  

Mechanism of circulating microparticles involving in atherosclerosis progress

作　　者：张颖倩 姜华[1] 孙鲁中 邹丽丽 佟潇 寇俊杰[1] ZHANG Ying-qian;JIANG Hua;SUN Lu-zhong;ZOU Li-li;TONG Xiao;KOU Jun-jie(Department of Cardiology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第二医院心内科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2018年第2期225-228,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：微粒是直径0.1~1.0μm的囊泡样结构。它是细胞在活化或凋亡后产生的,具有生理性和病理性的双重作用。循环微粒的水平在多种心血管疾病中是升高的。它在血浆中的升高被认为是血管功能改变的一个生物学标志。本篇综述旨在总结和提供循环微粒在动脉粥样硬化性炎症中扮演的角色的最新研究进展。Microparticles are vesicle-like structures with a diameter of 0.1 to 1.0μm.It′s produced after cell activation or apoptosis,which possesses physiological and pathological effects.Microparticle level rises in many cardiovascular diseases.Its elevation in plasma is thought to be a biomarker of vascular function change.The present article aimed at summarizing and providing newest research progress for microparticles playing role in atherosclerotic inflammation.

关 键 词：微粒体 动脉粥样硬化 炎症 

分 类 号：R543.509[医药卫生—心血管疾病]