乳腺超声及X线检查在鉴别乳腺导管原位癌是否伴微浸润中的价值  

Sonographic and mammographic features to distinguish DCIS and DCIS with microinvasion

作　　者：王红莉[1] 林锦江[2] 赖建国 顾然[1] 杨雅平[1] 谭翠[1] 刘凤桃 蒋小芳 胡越[1] 申时雨 梅静思 苏逢锡[1] WANG Hongli;LIN Jinjiang;LAI Jianguo;GU Ran;YANG Yaping;TAN Cui;LIU Fengtao;JIANG Xiaofang;HU Yue;SHEN Shiyu;SU Fengxi(Breast Tumor Center,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510289,China;Department of Radiology,The First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]中山大学孙逸仙纪念医院乳腺肿瘤中心,广州510289 [2]中山大学附属第一医院放射诊断专科,广州510080

出　　处：《岭南现代临床外科》2018年第2期146-149,共4页Lingnan Modern Clinics in Surgery

基　　金：国家自然科学基金面上项目(81672619)

摘　　要：目的比较导管原位癌(DCIS)及导管原位癌伴微浸润(DCISM)超声及X线特征的差异。方法经手术病理诊断为DCIS和DCISM的病例共147例(DCIS 94例,DCISM 53例)。超声上,病变分为肿块及非肿块。X线上,病变分为单纯钙化、肿块、局灶不对称或结构扭曲。统计分析采用χ~2检验,Fisher确切概率法及多因素logistic回归分析。结果单因素及多因素分析结果显示,超声上病变内可见钙化及血流提示DCISM可能(P=0.038,P=0.025)。此外,X线上钙化范围越大,DCISM可能性越高(P=0.002)。结论与DCIS相比,超声上病变内可见钙化及血流、X线上钙化分布范围较大与DCISM相关。Objective To compare the sonographic and mammographic features in patients with ductal carcinoma in situ(DCIS)and DCIS with microinvasion(DCISM).Methods A total of 147 women(94 DCIS and 53 DCISM)were retrospectively included.The sonographic lesions were classified as either masses or non-mass abnormalities.The lesions on mammography were classified as calcifications only,mass,asymmetry or architectural distortion.Statistical comparisons were made using Mann-W hitney U test,χ2 test,Fisher′s exact test and multiple logistic regression analysis.Results Univariate and multivariate analyses showed that the presence of microcalcifications and vascularity on sonography were associated with DCISM(P=0.038,P=0.025).Moreover,a greater range of calcification distribution were associated with a higher likelihood of DCISM(P=0.002).Conclusion The presence of microcal-cifications and vascularity on sonography or a great range of microcalcification distribution on mammo-graphy may suggest DCISM.

关 键 词：导管原位癌 微浸润 超声 乳腺X线摄影 

分 类 号：R445[医药卫生—影像医学与核医学]