婴幼儿反复呼吸道感染与维生素D缺乏的关系  

Relationship between recurrent respiratory infection and vitamin D deficiency in infants

作　　者：李东良 LI Dong-liang(Department of Pediatrics,Guidong People′s Hospital,Wuzhou 543000,China)

机构地区：[1]广西桂东人民医院儿科,梧州市543000

出　　处：《广西医学》2018年第7期756-758,共3页Guangxi Medical Journal

基　　金：广西医药卫生科研课题(Z20170997)

摘　　要：目的探讨婴幼儿反复呼吸道感染(RRI)与维生素D缺乏的关系。方法选择RRI婴幼儿200例(观察组)及非RRI婴幼儿100例(对照组),比较两组25-羟维生素D_3[25-(OH)D_3]水平及其缺乏发生率。对维生素D缺乏或不足的观察组患儿给予补充维生素D,比较治疗前后血清25-(OH)D_3水平及RRI发生情况。结果观察组不同年龄段患儿血清25-(OH)D_3水平均低于对照组,维生素D缺乏症发生率均高于对照组(P<0.05);补充维生素D后观察组各年龄段患儿25-(OH)D_3水平均高于治疗前,呼吸道感染发生次数减少(P<0.05)。结论维生素D缺乏可能与婴幼儿RRI发生有关,补充维生素D对预防RRI可能有一定的作用。Objective To explore the relationship between recurrent respiratory infection(RRI)and vitamin D deficiency in infants.Methods A total of 200 infants with RRI(observation group)and 100 infants without RRI(control group)were enrolled in the study.The level of 25-hydroxyvitamin D 3[25-(OH)D 3]and the incidence of 25-(OH)D 3 deficiency were compared between the two groups.The infants with vitamin D deficiency/insufficiency in the observation group were given vitamin supplement,and the level of serum 25-(OH)D 3 and the incidence of RRI before and after treatment were compared.Results In the observation group,the levels of serum 25-(OH)D 3 of infants with different ages were lower and the incidence rate of vitamin D deficiency was higher compared to those in the control group(P<0.05).After vitamin D supplement,the level of 25-(OH)D 3 of infants in all age groups was higher than that before treatment in the observation group,and the incidence of respiratory tract infection decreased(P<0.05).Conclusion Vitamin D deficiency may be associated with the incidence of RRI in infants,and vitamin D supplement might have a certain role in the prevention of RRI.

关 键 词：反复呼吸道感染 婴幼儿 维生素D 

分 类 号：R725.6[医药卫生—儿科]