3,6-二氯水杨醛的制备  

Preparation of 3,6-Dichlorosalicylaldehyde

作　　者：张玉才 ZHANG Yu-cai(College of Chemistry and Environmental Science,Kashgar University,Kashgar 844006,China)

机构地区：[1]喀什大学化学与环境科学学院,新疆喀什844006

出　　处：《宜春学院学报》2018年第3期25-26,52,共3页Journal of Yichun University

摘　　要：通过2,5-二氯苯酚和镁与甲醇生成的甲醇镁溶液反应生成2,5-二氯苯酚镁,接着2,5-二氯苯酚镁在多聚甲醛的作用下生成3,6-二氯水杨醛的镁盐,镁盐经酸化后得到目标产物3,6-二氯水杨醛。此方法反应时间为4 h,产率约89%,用GC-MS,1H NMR对该产物的结构进行了表征,与传统的甲酰化和阴极还原方法相比,该法效率高,原料廉价,因而良好的效益易达到工业生产的目的。2,5-dichlorophenol and magnesium and methanol generated by the reaction solution of methanol to 2,5-dichlorophenol magnesium in the role of paraformaldehyde generated 3,6-dichlorosalicylaldehyde magnesium salt and then the acidification of the product 3,6-dichlorosalicylaldehyde,compared with the traditional formylation and cathodic reduction method,it has high efficiency,low cost,and mainly this method is more efficient and the conditions required to achieve suitable for industrial production,Reaction 4 h,yield about 89%.the product was characterized by GC-MS and 1H NMR.

关 键 词：2 5-二氯苯酚 甲醇镁 多聚甲醛 3 6-二氯水杨酸 

分 类 号：O622[理学—有机化学]