血管内介入栓塞和开颅夹闭手术在颅内动脉瘤患者中的应用效果研究  

Effect of Intravascular Embolization and clipping surgery in patients with Intracranial Aneurysm

作　　者：吴毅 刘成辉[1] 陈旭[1] 肖胜辉[1] 梁世行[1] WU Yi;LIU Chenghui;CHEN Xu;XIAO Shenghui;LIANG Shihang(Department of Neurosurgery,Nanhai District People's Hospital,Foshan 528000,China)

机构地区：[1]广东省佛山市南海区人民医院神经外科,广东佛山528000

出　　处：《中国医药科学》2018年第7期213-216,共4页China Medicine And Pharmacy

摘　　要：目的对比分析血管内介入栓塞和开颅夹闭手术在颅内动脉瘤患者中的应用效果。方法选择2009年1月~2016年12月在本院确诊并住院治疗的60例颅内动脉瘤患者作为本次的研究对象,按照随机数字的原则分为实验组和对照组,每组30例,对照组使用开颅夹闭术,观察组使用血栓栓塞术治疗,对比分析两组患者的术后生活质量、手术时间、住院时间、住院费用、并发症的发生率、整体治疗效果。结果两组患者经过治疗以后,在躯体功能、认知功能、角色功能、社会功能、情绪功能等几方面的生活质量评分均明显高于治疗前,治疗前后比较差异有统计学意义(P<0.05),且实验组患者术后的评分明显高于对照组的患者,两组治疗后评分比较差异有统计学意义(P<0.05)。实验组患者手术时间及住院天数明显短于对照组的患者,两组比较差异有统计学意义(P<0.05);然而实验组患者发生的住院费用明显高于对照组的患者,两组比较差异有统计学意义(P<0.05)。实验组患者有26例患者有治疗效果,总有效率86.66%,对照组患者有20例患者有治疗效果,总有效率66.66%,两组患者治疗效果比较差异无统计学意义(P>0.05)。实验组有4例患者出现了并发症,发生率为13.33%,对照组有12例患者出现了并发症,发生率为40.00%,两组比较差异有统计学意义(P<0.05)。结论血管内介入栓塞术治疗颅内动脉瘤具有手术安全性高、治疗效果好的特点,但是手术费用昂贵及手术技术要求高,因此在治疗过程中需要综合考虑患者的经济水平以及医院的手术水平,针对不同的患者选择合适的手术治疗方法。Objective To compare the effect of endovascular embolization and clipping craniotomy in patients with intracranial aneurysms.Methods Sixty patients with intracranial aneurysms diagnosed and hospitalized in our hospital from January 2009 to December 2016 were selected as this study.According to the principle of random numbers,the patients were divided into the experimental group and the control group,with 30 cases in each group.The control group was treated with craniotomy,and the observation group was treated with thrombolytic embolization.The postoperative quality of life,the time of operation,the time of hospitalization,the hospitalization expenses,the incidence of complications and the effect of the overall treatment were compared and analyzed in the two groups.Results After treatment,the scores of body function,cognitive function,role function,social function and emotional function in the two groups were significantly higher than those before treatment(P<0.05).The postoperative scores of the patients in the experimental group were significantly higher than those in the control group,and the difference between the two groups after treatment was statistically significant(P<0.05).The operation time and hospitalization days of the patients in the experimental group were significantly shorter than those in the control group(P<0.05),but the hospitalization cost of the patients in the experimental group was significantly higher than that in the control group.The difference between the two groups was statistically significant(P<0.05).There were 26 patients in the experimental group,the total effective rate was 86.66,20 patients in the control group had the therapeutic effect and the total effective rate was 66.66.The difference between the two groups was not statistically significant(P>0.05).In the experimental group,4 patients had complications,the incidence was 13.33%.There were 12 cases of complications in the control group,the incidence was 40.00%.The difference between the two groups was statistically significan

关 键 词：开颅夹闭术 血管栓塞术 颅内动脉瘤 疗效分析 

分 类 号：R651.12[医药卫生—外科学]