低频脉冲电磁场联合阿仑膦酸钠治疗绝经后骨质疏松骨密度及骨代谢的影响  

Effects of low frequency pulsed electromagnetic fields combined with alendronate on bone mineral density and bone metabolism in postmenopausal osteoporosis

作　　者：郑黎勤[1] 郑衍庆 ZHENG Liqin;ZHENG Yanqing(Sanshui Hospital,Foshan Hospital of Traditional Chinese Medicine,Guangdong province,Foshan 528100,China)

机构地区：[1]广东省佛山市中医院三水医院,广东佛山528100

出　　处：《中国医药科学》2018年第7期247-250,共4页China Medicine And Pharmacy

摘　　要：目的观察低频脉冲电磁场联合阿仑膦酸钠治疗绝经后骨质疏松的疗效和安全性。方法将78例绝经后骨质疏松患者按随机数字表法分为试验组和对照组,对照组患者给予阿仑膦酸钠治疗,试验组在对照组的基础上加用低频脉冲电磁场,比较两组患者治疗效果。结果治疗4个月后,两组患者股骨颈、股骨粗隆、Wards三角和腰椎BMD水平,血清TRACP-5b、BAP、BGP水平以及VAS评分均较治疗前改善(P<0.05),试验组改善幅度大于对照组(P<0.05);试验组有效率明显高于对照组(P<0.05);两组不良反应发生率比较无统计学意义(P>0.05)。结论低频脉冲电磁场联合阿仑膦酸钠治疗绝经后骨质疏松效果肯定,安全性较好。Objective To observe the efficacy and safety of low frequency pulsed electromagnetic fields combined with alendronate in the treatment of postmenopausal osteoporosis.Methods Seventy-eight cases of postmenopausal osteoporosis were randomly divided into the experimental group and the control group.The patients in the control group were treated with alendronate,while the experimental group was added low frequency pulsed electromagnetic fields on the basis of the control group.The therapeutic effects of two groups were compared.Results After 4 months of treatment,the levels of femoral neck,trochanter,Wards triangle and lumbar BMD,the serum levels of TRACP-5b,BAP,BGP and VAS scores in the two groups were better than before treatment(P<0.05).The improvement of the experimental group was greater than that of the control group(P<0.05).The effective rate of the experimental group was significantly higher than that of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Low frequency pulsed electromagnetic field combined with alendronate sodium in the treatment of postmenopausal osteoporosis is effective and safe.

关 键 词：低频脉冲电磁场 阿仑膦酸钠 绝经后骨质疏松 

分 类 号：R580[医药卫生—内分泌]