8-(二苯基膦基)-7-甲基喹啉的合成与表征  

Synthesis and characterization of 8-( diphenylphosphino)-7-methylquinoline

作　　者：张文进[1] 刘立平[1] 陈布霖 魏琼[1] 柳利[1] ZHANG Wenjin;LIU Liping;CHEN Bulin;WEI Qiong;LIU Li(Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials(Hubei University), Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules(Hubei University),Wuhan 430062,China)

机构地区：[1]有机化工新材料湖北省协同创新中心(湖北大学),有机功能分子合成与应用教育部重点实验室(湖北大学),湖北武汉430062

出　　处：《湖北大学学报（自然科学版）》2018年第3期291-295,共5页Journal of Hubei University：Natural Science

基　　金：国家自然科学基金(21671061)资助

摘　　要：含喹啉单元的膦配体在有机光电材料中广受人们关注.本研究以间甲苯胺为原料,通过Skraup法制备7-甲基喹啉,然后利用N-溴代琥珀酰亚胺(NBS)上溴得到7-甲基-8-溴喹啉后,与正丁基锂反应得到有机锂中间体,最后与二苯基氯化膦反应得到目标化合物8-(二苯基膦基)-7-甲基喹啉.采用核磁共振(1H、31P、13C NMR)、傅里叶变换红外光谱(FT-IR)、液质联用飞行时间质谱(LC-MS TOF)等对目标化合物的结构进行了表征,为后续设计发光金属配合物提供重要前体.该化合物目前还鲜见报道.该合成路线具有原料成本低、操作简便和产率较高的优点.The phosphine ligands containing quinoline units have receievd much attention in organic photoelectric materials.In this paper,7-methylquinoline was prepared by Skraup method using m-toluidine as raw material,and then 7-methyl-8-bromoquinoline was obtained by reaction with N-bromosuccinimide(NBS).Then 7-methyl-8-bromoquinoline was reacted with n-butyllithium to get lithium reagent and then reacted with diphenylphosphine chloride to obtain the target compound 8-(diphenylphosphino)-7-methylquinoline.The structure of the target compound was characterized by NMR(1 H,31 P,13 C),Fourier transform infrared spectroscopy(FT-IR)and LC-MS TOF spectra.It provided a precursor for synthesis of luminescent metal complexes in the further step.As far as we know,this compound has been few reported.This synthetic scheme has advantages of low cost,convinent process and high yields.

关 键 词：喹啉 膦配体 发光材料 合成 表征 

分 类 号：O626[理学—有机化学]