新型氮杂环卡宾-钌(Ⅱ)催化剂的合成及催化活性  

Synthesis and Catalytic Activity of A Novel N-heterocyclic Carbene Ruthenium(Ⅱ) Catalyst

作　　者：田福宁 韩洁 刘治国 黄晴菲[2] 王启卫[2] TIAN Fu-ning;HAN Jie;LIU Zhi-guo;HUANG Qing-fei;WANG Qi-wei(College of Science,Xihua University,Chengdu 610039,China;Chengdu Institute of Organic Chemistry,Chinese Academy of Sciences,Chengdu 610041,China)

机构地区：[1]西华大学理学院,四川成都610039 [2]中国科学院成都有机化学研究所,四川成都610041

出　　处：《合成化学》2018年第4期250-255,共6页Chinese Journal of Synthetic Chemistry

基　　金：中国科学院“西部之光”人才培养计划

摘　　要：以1,3-双(2,6-二异丙基苯基)咪唑鎓盐酸盐(IPr HCl,4a)或1,3-双[2,6-二(1-乙基丙基)苯基]咪唑鎓盐酸盐(IPent·HCl,5a),及Grubbs第一代催化剂和2-异丙氧基苯乙烯为原料,经去质子化反应和烯烃复分解反应合成了两种新型的NHC-钌催化剂4c和5c,其结构经~1H NMR,^(13)C NMR和HR-MS(ESI)表征。并研究了4 c和5c的性能。结果表明:4c和5c的稳定性较好,对关环复分解反应有良好的催化活性。Using 1,3-bis(2,6-diisopropylphenyl)-imidazolidinium chloride(IPrHCl,4a),or 1,3-bis[2,6-bis(1-ethylpropyl)phenyl]imidazolium chloride(IPentHCl,5a),Grubbs first generation catalyst and 1-isopropoxy-2-vinylbenzene as raw materials,two novel NHC-ruthenium complexes(4c,IPrRuCl 2)and(5c,IPentRuCl 2)were synthesized via deprotonation and olefin metathesis reaction.The structures were characterized by 1 H NMR,13 C NMR and HR-MS(ESI).And the properties of 4c and 5c were investigated as well.The results showed that 4c and 5c exhibited high catalytic activity at low dosage with fast initiation rate and high stability in ring-closing metathesis reaction.

关 键 词：氮杂环卡宾 Grubbs催化剂 关环复分解反应 合成 催化活性 

分 类 号：O626.2[理学—有机化学]