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作 者:程萍[1] 杨飚 Cheng Ping;Yang Biao(Department of Gynaecology,Taihe Hospital Affiliated to Hubei Medical College,Shiyan 442000)
机构地区:[1]湖北医药学院附属太和医院妇科,十堰442000
出 处:《陕西医学杂志》2018年第5期571-573,576,共4页Shaanxi Medical Journal
摘 要:目的:探讨输卵管处理方案选择对行腹腔镜全子宫切除术患者手术相关临床指标、激素及MPS发生率的影响。方法:选取腹腔镜全子宫切除术患者共130例,以随机数字表法分为A组(65例)和B组(65例),分别行双侧输卵管保留和彻底切除方案治疗;比较两组患者手术相关临床指标水平,治疗前后血清性激素和抗苗勒管激素水平,围绝经期综合征(MPS)发生率。结果:两组患者手术相关临床指标水平比较差异无统计学意义(P>0.05);两组患者治疗后FSH和LH水平均显著高于治疗前(P<0.05);两组患者治疗后E2水平显著低于治疗前(P<0.05);两组患者治疗后抗苗勒管激素水平均显著低于治疗前(P<0.05);但两组患者治疗后性激素和抗苗勒管激素水平比较差异无统计学意义(P>0.05);同时两组患者术后3个月和6个月MPS发生率比较差异无统计学意义(P>0.05)。结论:行腹腔镜全子宫切除术患者术中切除双侧输卵管后并未影响术后激素水平和MPS发生风险,故围绝经期女性或合并卵巢癌高危因素者应首选同期双侧输卵管切除。Objective:To investigate the influence of ovarian ducts processing scheme chosen on the operation-related clinical indicators,hormone and MPS incidence of patients undergoing laparoscopic total hysterectomy.Methods:130 patients undergoing laparoscopic total hysterectomy were divided into two groups including control group(65 patients)with bilateral tubal retain and observation group(65 patients)with bilateral tubal resection;and the operation-related clinical indicators,the levels of serum sex hormone and anti mullerian hormone before and after treatment and the MPS incidence of both groups were compared.Results:There was no significant difference in the levels of operation-related clinical indicators between 2 groups(P>0.05).The levels of FSH and LH of both groups after treatment were significant higher than control group(P<0.05).The levels of E2 of both groups after treatment were significant lower than control group(P<0.05).The levels of AMH of both groups after treatment were significant lower than before treatment(P<0.05).There was no significant difference in the levels of serum sex hormone and anti mullerian hormone after treatment between 2 groups(P>0.05).There was no significant difference in the MPS incidence in 3 months and 6 months after treatment between 2 groups(P>0.05).Conclusion:Bilateral salpingectomy in the treatment patients undergoing laparoscopic total hysterectomy have no effect on the hormone level and MPS risk;and simultaneous resection of bilateral fallopian tube are recommended to the perimenopausal women and ovarian cancer risk factors patients.
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