长期肝内胆管结石患者肝胆管癌变的临床特征和疗效及预后分析  

The analysis of characteristic and Prognosis of hePatic duct canceration of long-term hePatolith Patients

作　　者：张波[1] ZHANG Bo(DePartment of general surgery,Sichuan Province Chengdu city the Fifth PeoPle's HosPital,Sichuan Chengdu 611130,China)

机构地区：[1]四川省成都市第五人民医院普外科,四川成都611130

出　　处：《临床医药文献电子杂志》2017年第55期10765-10766,共2页Electronic Journal of Clinical Medical Literature

基　　金：成都市卫计委科研资助项目(编号2015194)

摘　　要：目的长期肝内胆管结石患者肝胆管癌变的临床特征和疗效及预后分析。方法选取我院18例经确诊的肝内胆管结石肝胆管癌变患者作为观察组,另选取同期20例单纯肝内胆管结石患者作为对照组,对比两组患者临床症状、疗效以及预后。结果观察组患者临床症状主要表现为腹痛、发热、肝区叩击痛、黄疸等,和对照组相比无明显差异,P>0.05;观察组白细胞、肝酶增高、HBs Ag(+)、肝内占位性病变高于对照组,P<0.05;观察组内镜引流及内支架植入术较少,开腹手术与肝切除手术较多,和对照组相比有明显差异,P<0.05;观察组肝内占位病变直径>5cm患者多于对照组,围术期死亡率以及术后1年、3年、5年存活率均低于对照组,P<0.05。结论长期肝内胆管结石患者肝胆管癌变的临床症状主要表现为腹痛、发热、肝区叩击痛、黄疸等,临床一般通过肝切除术进行治疗,能有效延长患者生存时间,值得在临床推广应用。Objective To discuss the analysis of characteristic and Prognosis of hePatic duct canceration of long-term hePatolith Patients.Methods Choosed 18 cases of hePatic duct canceration of long-term hePatolith Patients as study grouP,and choosed 20 cases of hePatolith Patients as controlled grouP.ComPared the clinical effect and Prognosis.Results The symPtom of study grouP were abdominal Pain,fever,hePatocalgia and jaundice,with no difference with controlled grouP(P>0.05).And the leukocyte,hePatic enzyme increased,HBsAg(+),hePatic astrological disease of study grouP were all higher than controlled grouP(P<0.0.5).Adn the cases of laParotomy of study grouP was higher than controlled grouP(P<0.05).And the cases of liver occuPying more than 5cm of study grouP were more than onntrolled grouP and the survival rate in 1,3,5 years of study grouP were all lower than controlled grouP(P<0.05).Conclusion The symPtom of hePatic duct canceration of long-term hePatolith Patients were abdominal Pain,fever,hePatocalgia and jaundice,and we can use hePatectomy to let them survival longer.

关 键 词：肝内胆管结石 肝胆管癌变 临床特征 预后 

分 类 号：R657[医药卫生—外科学]