尤瑞克林对急性脑梗死疗效观察及对CPR的影响研究  

The Effect of Yuklin on Acute Cerebral Infarction and Its Influence on CPR

作　　者：张建娥[1] ZHANG Jian-e(Department of Neurology Sanmenxia Central Hospital,Sanmenxia Henan 472000,China)

机构地区：[1]三门峡市中心医院神经内科,河南三门峡472000

出　　处：《药品评价》2018年第11期38-40,共3页Drug Evaluation

摘　　要：目的:探讨尤瑞克林对急性脑梗死疗效观察及对CPR的影响。方法:回顾2015年2月至2017年1月急性脑梗死患者90例以治疗方法分组。对照组给予常规对症方法治疗,观察组则在对照组基础上增加尤瑞克林治疗。比较两组急性脑梗死临床治疗效果;住院天数;治疗前后患者全血黏稠度、血小板聚集率、血清尿酸水平、C反应蛋白水平;治疗前后患者神经功能缺损评分、功能独立水平;不良反应发生率。结果:观察组急性脑梗死临床治疗效果高于对照组,P<0.05;观察组住院天数短于对照组,P<0.05;治疗前两组全血黏稠度、血小板聚集率、血清尿酸水平、C反应蛋白水平相近,P>0.05;治疗后观察组全血黏稠度、血小板聚集率、血清尿酸水平、C反应蛋白水平优于对照组,P<0.05。治疗前两组神经功能缺损评分、功能独立水平相近,P>0.05;治疗后观察组神经功能缺损评分、功能独立水平优于对照组,P<0.05。观察组不良反应发生率和对照组相近,P>0.05。结论:尤瑞克林对急性脑梗死疗效确切,可有效改善神经功能,改善血液流变学指标,还可减低尿酸水平和CPR,改善患者预后,缩短住院时间,且药物无明显不良反应,耐受性好。Objective:To investigate the effect of eucrine on acute cerebral infarction and CPR.Methods:90 patients with acute cerebral infarction from February 2015 to January 2017 were randomly divided into groups.The control group was treated with routine symptomatic therapy,while the observation group was treated with eucrine on the basis of the control group.The clinical treatment effect,hospitalization days,whole blood viscosity,platelet aggregation rate,serum uric acid level and C-reactive protein level were compared between the two groups before and after treatment,and the neurological deficit score and functional independence level before and after treatment were compared.Incidence of adverse reactions was also compared.Results:The clinical therapeutic effect was higher in observation group than that of the control group(P<0.05).The hospitalization days of the observation group were shorter than those in the control group(P<0.05).The blood viscosity,platelet aggregation rate,serum uric acid level and C-reactive protein level were similar in both groups before and after treatment,P>0.05;After treatment,the whole blood viscosity,platelet aggregation rate,serum uric acid level and C-reactive protein level were better than those in the control group(P<0.05).After treatment,the score of neurological deficit was better than that of the control group(P<0.05).The rate was similar to that of the control group(P>0.05).Conclusion:Urikline is effective in the treatment of acute cerebral infarction.It can effectively improve nerve function,improve hemorheology,decrease uric acid level and CPR,improve prognosis,shorten hospital stay,and have no obvious adverse drug reactions.

关 键 词：尤瑞克林 急性脑梗死 CPR 

分 类 号：R971[医药卫生—药品]