慢性丙型肝炎的治愈之路  

Approach to cure chronic hepatitis C

作　　者：纪冬[1] 陈国凤[1] JI Dong;CHEN Guo-feng(Second Liver Cirrhosis Diagnosis and Treatment Center,302 Military Hospital of China,Beijing 100039,China)

机构地区：[1]解放军第三○二医院肝硬化诊疗二中心,北京100039

出　　处：《传染病信息》2018年第3期199-202,208,共5页Infectious Disease Information

基　　金：中华医学会临床医学科研专项基金(13071110496)

摘　　要：HCV是慢性肝病的致病因素之一,自从直接抗病毒药物(direct-acting antiviral agent,DAA)相继上市以来,慢性丙型肝炎的治疗领域发生了迅猛的变化,所有慢性丙型肝炎患者似乎都可以通过DAA来"治愈"。然而我们也必须清楚的意识到HCV的清除并不能代表慢性HCV感染相关性肝病的治愈,本文就治愈丙型肝炎道路上面临的机遇与挑战作一评述。Hepatitis C virus is a major cause for chronic liver diseases.The treatment of chronic hepatitis C(CHC)has been changing rapidly since direct-acting antiviral agent(DAA)is subsequently approved for market.CHC patients at all stages can almost be“cured”by DAA.However,we must realize that the eradication of CHC infection doesn't mean the curing of CHC-related liver diseases.This paper aims to review the challenges of opportunities of the approach to cure CHC.

关 键 词：丙型肝炎 直接抗病毒药物 肝细胞癌 

分 类 号：R512.91[医药卫生—内科学]