糖皮质激素治疗甲亢伴浸润性突眼的疗效分析  

Efficacy of Glucocorticoids in the Treatment of Hyperthyroidism with Infiltrating Exophthalmos

作　　者：康凯[1] 郑继伟[1] 王闰[1] KANG Kai;ZHENG Ji-wei;WANG Run(Department of Ophthalmology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)

机构地区：[1]佳木斯市中心医院眼科,黑龙江佳木斯154002

出　　处：《医学信息》2018年第8期103-104,共2页Journal of Medical Information

摘　　要：目的分析使用糖皮质激素分期治疗甲亢伴浸润性突眼的的临床疗效和不良反应发生率。方法选取自2015年5月30日~2017年4月30日来我院接受治疗的甲亢伴浸润性突眼的患者64例,随机分为观察组和对照组,每组32例。对照组采用常规131I进行传统治疗,观察组采用糖皮质激素治疗,对比两组患者的疗效和不良反应发生率。结果观察组总有效率为93.75%,高于对照组的68.75%,差异具有统计学意义(P<0.05)。观察组不良反应发生率为71.88%,高于对照组的15.63%,差异具有统计学意义(P<0.05)。结论应用糖皮质激素治疗甲亢伴浸润性突眼症,能够从一定程度上大幅度缩短治疗时间,但是其不良反应过于剧烈,使患者在治疗方面获得一定的不良体验。Objective To analyze the clinical efficacy and incidence of adverse reactions in the treatment of hyperthyroidism with infiltrating exophthalmos using glucocorticoids.Methods 64 patients with hyperthyroidism and infiltrating exophthalmos who were treated in our hospital from May 30,2015 to April 30,2017 were randomly divided into observation group and control group,with 32 cases in each group.In the control group,conventional 131I was used for traditional treatment,and observation group was treated with glucocorticoids.The efficacy and incidence of adverse reactions were compared between the two groups.Results The total effective rate was 93.75%in the observation group,which was higher than 68.75%in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 71.88%,which was higher than that in the control group 15.63%,the difference was statistically significant(P<0.05).Conclusion Treatment of hyperthyroidism with infiltrating exophthalmos with glucocorticoids can shorten the treatment time to a certain extent,but the adverse reactions are too severe,so that patients receive certain adverse experiences in the treatment.

关 键 词：糖皮质激素 甲亢 浸润性突眼 

分 类 号：R581.1[医药卫生—内分泌]