黄石市中心医院2006-2016年抗肿瘤中药注射剂不良反应回顾性分析  

Retrospective Analysis on ADR Induced by Anti-tumor TCM Injections in Huangshi Central Hospital from 2006 to 2016

作　　者：伍延婷 金星[1] WU Yan-ting;JIN Xing(Department of Pharmacy,Huangshi Central Hospital of Edong Healthcare Group,Huangshi 435001,China)

机构地区：[1]鄂东医疗集团黄石市中心医院药学部,湖北黄石435001

出　　处：《中国中医药信息杂志》2018年第8期126-128,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的探讨抗肿瘤中药注射剂不良反应发生的特点与规律,为临床合理用药提供参考。方法采用病历回顾性研究方法,对黄石市中心医院(以下简称"本院")2006年1月-2016年6月填报的73例抗肿瘤中药注射剂药物不良反应(ADR)报告进行统计分析。结果 73例ADR报告中,中老年患者发生比例最高;涉及药品种类排序前3位的为复方苦参注射液、参麦注射液和艾迪注射液;ADR累及系统/器官以全身性损害最常见,其次为消化系统和皮肤及其附件损害;发生时间主要集中在用药当日,特别是用药后30 min内。结论本院应重视抗肿瘤中药注射剂ADR监测工作,提高临床合理用药水平。Objective To investigate the characteristics and regularity of adverse drug reactions(ADR)induced by anti-tumor TCM injections;To provide references for rational use of medicine in clinic.Methods Totally 73 ADR reports induced by anti-tumor TCM injections in Huangshi Central Hospital from January 2006 to July 2016 were retrospectively analyzed(hereinafter referred to as“our hospital”).Results Among 73 ADR reports,the elderly patients had the highest proportion;the top 3 kinds of medicine involved were compound Kushen Injection,Shenmai Injection and Addie Injection;the most common ADR involved the damages on systemic lesion,digestive system and skin and its appendages;the time of occurrence mainly concentrated on the day of medication,especially after 30 min.Conclusion The monitoring of anti-tumor TCM injections of ADR should be strengthened in our hospital,to improve the level of rational medicine use.

关 键 词：中药注射剂 抗肿瘤 不良反应 合理用药 

分 类 号：R288[医药卫生—中药学]