分子印迹技术原理及在标准物质定值中的应用  

The Principle of Molecularly Imprinted Technology and Its Application in Standard Material Determination

作　　者：张红杰[1] 郭知明[1] Zhang Hongjie;Guo Zhiming(Tianjin Metrological Supervision and Inspection Scientific Research Institute,Tianjin,300192,China)

机构地区：[1]天津市计量监督检测科学研究院,天津300192

出　　处：《仪器仪表用户》2018年第9期55-57,共3页Instrumentation

基　　金：天津市市场和质量监督管理委员会科技计划资助项目(2018-W32)

摘　　要：分子印迹技术是制备具有特异预定选择性的高分子化合物——分子印迹聚合物的技术,也是当前分析化学领域研究的热点。该技术是模仿钥匙的原理,即在印迹分子(模板)存在的条件下,在模板周围合成特定聚合物,之后将模板移出,形成特定孔穴。它具有高选择性、分子识别、可具有针对性设计等特点,表现出较高的应用潜力。在标准物质定值当中多组分分离、痕量组分富集是研究的难点,而这却是分子印迹技术的优势,因而分子印迹技术在标准物质定值工作中具有很高的应用价值。Molecular imprinting is a technique for preparing polymer with specific predetermined selectivity.The technique mimics the key principle of synthesizing a specific polymer around the template in the presence of imprinted molecules(templates)and then removing the template to form a specific hole.It has the characteristics of high selectivity,molecular recognition and targeted design,showing high application potential.In standard set material as multicomponent separation and enrichment of trace components is a key problem for study,and this is the advantage of molecular imprinting technique and molecularly imprinted technique in the standard material constant value work has the very high application value.

关 键 词：分子印迹技术 分子印迹聚合物 标准物质 

分 类 号：R917[医药卫生—药物分析学]