五苓散治疗蓄水证与水通道蛋白1关系的研究进展  

A review on the relationship between treating stagnated fluid syndrome with Wuling San and AQP1

作　　者：陈利娜 郭澜 孙世晓[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医临床研究》2018年第17期135-137,共3页Clinical Journal Of Chinese Medicine

摘　　要：五苓散出自张仲景的《伤寒论》,是温阳化气利水的经典名方。自古到今,在治疗水液代谢方面的疾病,一直都有着显著的疗效。水通道蛋白1(AQP1)是水通道蛋白家族之一,其分布于多种组织器官中,主要是与水液代谢调节相关的组织器官。水通道蛋白(AQPs)的出现为五苓散利水作用机制提供了新的研究方向。现在虽对AQP1的研究比较充足,但AQP1表达与五苓散的关系研究比较缺乏。根据五苓散治疗蓄水证和蓄水证对AQP1的关系,推断五苓散可能影响AQP1的表达。Wuling San(五苓散)from Shanghan Lun(《伤寒论》)written by Zhang Zhongjing,is the classical prescription of Wenyang Huaqi Lishui(温阳化气利水).Since ancient times,Wuling San on the disease of metabolism of the body fluidon shows a significant effect.AQP1 is one of the aquaporin,and is distributed in a variety of tissues and organs,mainly related to the regulation of metabolism of the body fluidon.The AQPs provides a new research direction for the mechanism of Lishui(利水)of Wuling San.Although the research on AQP1 is sufficient now,the relationship between the expression of AQP1 and Wuling San lacked.According to the treatment of stagnated fluid syndrome with Wuling San and the relationship between stagnated fluid syndrome and AQP1,it is concluded that Wuling San may affect the expression of AQP1.

关 键 词：五苓散 蓄水证 AQP1 

分 类 号：R242[医药卫生—中医临床基础]