应用T_2 mapping及CUBE序列观察盘状软骨对发育性髋关节发育不良关节软骨的影响  

The effect of libmus on hip cartilage of patients with hip developmental dysplasia: Evaluation using T_2 mapping and CUBE

作　　者：孟祥虹[1] 王植[1] 杨建平[2] 张中礼[2] 郭林[1] 张雪宁[3] MENG Xianghong;WANG Zhi;YANG Jianping;ZHANG Zhongli;GUO Lin;ZHANG Xuening(Department of Radiology,Tianjin Hospital,Tianjin 300211,China;Department of Orthopedic Pediatrics,Tianjin Hospital,Tianjin 300211,China;Department of Radiology,the Second Hospital of Tianjin Medical University)

机构地区：[1]天津市天津医院放射二科,天津300211 [2]天津市天津医院小儿骨科,天津300211 [3]天津医科大学第二医院放射科

出　　处：《国际医学放射学杂志》2018年第4期396-400,共5页International Journal of Medical Radiology

摘　　要：目的应用T_2mapping和CUBE序列探讨盘状软骨对发育性髋关节发育不良(DDH)病人关节软骨的影响。方法连续收集2015年10月—2017年6月经X线诊断为DDH或因髋关节不适来我院就诊并行MRI检查的年龄≤5岁的56例患儿,男13例,女43例,年龄2~60个月,平均年龄(24.6±10.3)个月。将所有患儿分为3组:组1,有DDH和盘状软骨者(18例);组2,有DDH无盘状软骨者(21例);组3,无DDH者(17例)作为对照组。应用冠状面T_2 mapping序列计算髋臼及股骨头侧关节软骨的T_2值,并在冠状面T_2 CUBE序列及横断面、矢状面重组影像上测量盘状软骨的径线。采用单因素方差分析比较3组间关节软骨T_2值的差异,采用线性回归分析组1盘状软骨体积对关节软骨T_2值的影响。结果组1的髋臼侧关节软骨的T_2值大于组2、组3(均P<0.05),组2和组3 T_2值的差异无统计学意义(P>0.05)。组1的股骨头侧关节软骨的T_2值大于组3(P<0.05),其余组间的T_2值差异均无统计学意义(均P>0.05)。盘状软骨体积增大,组1病人髋臼侧(Y=47.759+0.027X,R^2=0.840)及股骨头侧(Y=43.929+0.022X,R^2=0.269)关节软骨的T_2值增加。结论应用T_2 mapping和CUBE序列可发现盘状软骨阻碍DDH病人髋关节软骨的发育。Objective To study whether the limbus in patients with developmental dysplasia of the hip(DDH)has effect on the development of the articular cartilage of hips,using T2 mapping and CUBE.Methods From October 2015 to June 2017,we consecutively collected 56 children who showed DDH on radiography or complainted hip discomfort.All the subjects were≤5-year-old and performed MR examination,including 13 boys and 43 girls,aged 24.6±10.3 months(range 2-60 months).The subjects were subdivided into three groups,group1:The patients with DDH and limbus(18 patients),group 2:The patients with DDH without limbus(21 patients),and group 3:The controls,who had no DDH(17 patients).Coronal T2 mapping was utilized to calculate the T2 values of the cartilage in acetabuli and femoral heads of hip joints.Coronal T2 CUBE and transverse and sagittal reformation images were used to measure the diameters of the limbus.Statistics differences of T2 values of cartilage of hip joints among the three groups were analyzed by Oneway-ANOVA.The effect of the volume of the limbus on the T2 values of the cartilage of the hip joints in patients of group 1 was analyzed by lineal regression analysis.Results The T2 values were significantly higher in the group 1 than in the group 2 and group 3(all P<0.05).The T2 values between the 2 and 3 groups showed no significant difference(P>0.05).The T2 values were significantly higher in the group 1 than in the group 3(P<0.05),and there was no significant difference in T2 value of cartilage of femoral heads between other groups(P>0.05).The increase of the limbus volume was associated with the increasesd T2 values of cartilage of acetabula(Y=47.759+0.027X,R2=0.840)and femoral heads(Y=43.929+0.022X,R2=0.269)in the group 1.Conclusion Using T2 mapping and CUBE can identify that the limbus impedes the development of the cartilage of hip joints in patients with DDH.

关 键 词：盘状软骨 发育性髋关节发育不良 T2 MAPPING 三维快速自旋回波-CUBE 

分 类 号：R726.8[医药卫生—儿科] R445.2[医药卫生—临床医学]