CMR新技术在心肌纤维化的研究进展及与LGE-MRI的比较  

Research progress of new cardiac magnetic resonance techniques in myocardial fibrosis and comparison with late gadolinium enhancement MRI

作　　者：张倩[1] 宋林声 赵新湘[1] ZHANG Qian;SONG Linsheng;ZHAO Xinxiang(Department of Radiology,Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China)

机构地区：[1]昆明医科大学第二附属医院磁共振室,昆明650101

出　　处：《国际医学放射学杂志》2018年第4期419-421,463,共4页International Journal of Medical Radiology

基　　金：云南省科技计划项目[2017FE468(-178)]

摘　　要：心肌纤维化(MF)是心室重塑及恶性心律失常发生的根本原因,最终可导致心功能不全、猝死等主要心脏不良事件的发生。延迟增强MRI(LGE-MRI)是既往心肌梗死后局限性MF检测的临床应用标准,而当今T_1 mapping技术在对心肌弥漫性MF的检测和定量评价中更具优势,心脏功能MRI技术如扩散张量成像(DTI)和扩散加权成像(DWI)无需对比剂即可定量评估心肌微细结构,在MF检测方面亦表现出较大的应用潜能。综述T_1 mapping、DTI、DWI等技术进展并与LGE-MRI进行比较。Myocardial fibrosis(MF)is the root cause of ventricular remodeling and malignant arrhythmia.It eventually leads to the occurrence of major cardiac adverse events such as cardiac insufficiency and sudden death.Late gadolinium enhancement MRI(LGE-MRI)is a standard method in clinical setting for the detection of focal MF following myocardial infarction.T1 mapping has more advantages than LGE-MRI in the detection and quantitative evaluation of diffuse MF.Cardiac functional MRI such as diffusion tensor imaging(DTI)and diffusion weighted imaging(DWI)can be used to quantitatively assess myocardial micro-structures without using contrast media.DTI and DWI have shown great potentials in the detection of MF.This article reviews the progress of T1 mapping,DTI,DWI,and compare them with LGE-MRI.

关 键 词：心肌纤维化 磁共振成像 延迟增强 T1 MAPPING T1ρmapping 扩散张量成像 扩散加权成像 

分 类 号：R541[医药卫生—心血管疾病] R445.2[医药卫生—内科学]